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Expression of vascular endothelial growth factor‐C in human hepatocellular carcinoma

Journal of Gastroenterology and Hepatology, 2006
AbstractBackground/Aims:  Vascular endothelial growth factor‐C (VEGF‐C) is thought to be an important factor in tumor angiogenesis/lymphangiogenesis, but its role in hepatocellular carcinoma (HCC) has not yet been fully investigated.Methods:  We immunohistochemically examined VEGF‐C expression in surgically resected tissues of 90 HCC.Results:  In the ...
Rin, Yamaguchi   +6 more
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Role of vascular endothelial growth factor C in classical Hodgkin lymphoma

Leukemia & Lymphoma, 2015
We performed three different studies to obtain additional data on the biological and prognostic role of vascular endothelial growth factor C (VEGFC) in classical Hodgkin lymphoma (cHL): (1) serum VEGFC levels were measured by enzyme-linked immunosorbent assay in 80 patients; (2) immunohistochemical VEGFC expression in tumor tissue was evaluated using a
Antonio, Rueda   +10 more
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Mechanism of Dimerization of a Recombinant Mature Vascular Endothelial Growth Factor C

Biochemistry, 2013
The vascular endothelial growth factors (VEGFs) and their tyrosine kinase receptors play a pivotal role in angiogenesis and lymphangiogenesis during development and in pathologies such as tumor growth. The VEGFs function as disulfide-linked antiparallel homodimers.
Gerometta, Michael   +3 more
openaire   +4 more sources

Serum vascular endothelial growth factor-C and vascular endothelial growth factor level in patients with colorectal carcinoma and clinical significance

Journal of Huazhong University of Science and Technology [Medical Sciences], 2006
Circulating vascular endothelial growth factor-C (VEGF-C) and vascular endothelial growth factor (VEGF) levels in patients with colorectal carcinoma were determined in order to assess their clinical significance as a diagnostic tool for monitoring lymph node metastasis.
Tianwen, Xu, Daoda, Chen
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[Prokaryotic expression of vascular endothelial growth factor-C].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2004
To evaluate whether the vascular endothelial growth factor (VEGF)-C cDNA which cloned from a patient with squamous cell carcinoma (SCC) of tongue can encode a functional protein or not.RT-PCR was employed to clone the functional VEGF-C fragment from the surgical specimen of a lingual SCC patient.
Jian, Pan, Yuming, Wen, Chengge, Hua
openaire   +1 more source

Artemisinin Inhibits Tumor Lymphangiogenesis by Suppression of Vascular Endothelial Growth Factor C

Pharmacology, 2008
We have previously reported that dihydroartemisinin is found to have a potent ability in influencing lymphatic endothelial cell migration and tube formation. In this study, we investigated the effect of artemisinin on tumor growth, lymphangiogenesis, metastasis and survival in mouse Lewis lung carcinoma (LLC) models.
Jun, Wang   +7 more
openaire   +2 more sources

Vascular Endothelial Growth Factor–C (VEGF-C) Expression in Normal Human Tissues

Lymphatic Research and Biology, 2006
To characterize vascular endothelial growth factor-C (VEGF-C) protein expression in normal human tissues by immunohistochemistry (IHC). VEGF-C is a growth factor for lymphatic endothelial cells. VEGF-C mRNA and protein are expressed in a variety of cancerous tissues, but the localization of VEGF-C protein in many normal human tissues has not been ...
K D, Joory   +3 more
openaire   +2 more sources

Expression of vascular endothelial growth factor-C and its receptor in osteosarcomas

Pathology - Research and Practice, 2008
Vascular endothelial growth factor-C (VEGF-C) and its receptor, vascular endothelial growth factor receptor-3 (VEGFR-3), have been implicated as important factors in the formation of lymphatic vessels, but its role in osteosarcomas has not yet been fully investigated.
Hye-Rim, Park   +4 more
openaire   +2 more sources

Src contributes to IL6-induced vascular endothelial growth factor-C expression in lymphatic endothelial cells

Angiogenesis, 2013
Formation of lymphatic capillaries by lymphatic endothelial cells (LECs) occurs both in normal tissues as well as in pathological processes including tumor metastasis. Interleukin-6 (IL-6), a potent pro-inflammatory cytokine, has been shown to be highly elevated in various cancers.
Yu-Han, Huang   +5 more
openaire   +2 more sources

Quantification of Vascular Endothelial Growth Factor-C

Journal of Immunological Methods, 2004
Abdul Fattah Al-Mowallad   +6 more
openaire   +1 more source

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