Results 91 to 100 of about 724,253 (297)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization [PDF]
, 2011 Angiogenesis, or neovascularization, is a finely balanced process controlled by pro- and anti-angiogenic factors. Vascular endothelial growth factor (VEGF) is a major pro-angiogenic factor, whereas pigment epithelial-derived factor (PEDF) is the most ...
Crawford, Ross, Fan, Wei, Xiao, Yin
core +2 more sources
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Tumor Biology, 2017 The matrix metalloproteinase-9, E-cadherin, and vascular endothelial growth factor play an important role in behavior of tumor cell growth, invasion, and metastasis.
Hongyu Gao +3 more
doaj +1 more source
Vascular Endothelial Growth Factor Levels in Patients with Hypothyroidism
Mìžnarodnij Endokrinologìčnij Žurnal, 2015 The objective of the investigation was to determine the levels of vascular endothelial growth factor in patients with primary hypothyroidism. Having examined 133 patients with manifested hypothyroidism, we discovered that levels of vascular endothelial ...
O.M. Didushko
doaj +1 more source
Composite Hydrogels with the Simultaneous Release of VEGF and MCP-1 for Enhancing Angiogenesis for Bone Tissue Engineering Applications [PDF]
, 2018 Rapid new microvascular network induction was critical for bone regeneration, which required the spatiotemporal delivery of growth factors and transplantation of endothelial cells.
Chang, Pengbo +9 more
core +1 more source
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Effects of Hypothyroidism Treatment on the Level of Vascular Endothelial Growth Factor
Mìžnarodnij Endokrinologìčnij Žurnal, 2015 The objective of the investigation is identifying the level of vascular endothelial growth factor in patients with primary hypothyroidism and influence of complex treatment on its levels. Materials and methods.
O.M. Didushko
doaj +1 more source
The discovery of angiogenic growth factors: the contribution of Italian scientists [PDF]
, 2014 Angiogenesis is regulated, under both physiological and pathological conditions, by numerous “non-classic” pro-angiogenic factors, including fibroblast growth factor-2 (FGF-2), vascular endothelial growth factor (VEGF), and placental growth factor (PlGF),
Domenico Ribatti
core +1 more source
Arthritis Care &Research, EarlyView.Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler +8 more
wiley +1 more source