Results 71 to 80 of about 724,253 (297)

Correlation between vascular endothelial growth factor expression and presence of lymph node metastasis in advanced squamous cell carcinoma of the larynx

Brazilian Journal of Otorhinolaryngology, 2015
Introduction: Squamous cell carcinoma is the most common neoplasm of the larynx, and its evolution depends on tumor staging. Vascular endothelial growth factor is a marker of angiogenesis, and its expression may be related to increased tumor ...
Rodrigo Gonzalez Bonhin, Vanessa Brito Campoy Rocha, Guilherme Machado de Carvalho, Alexandre Caixeta Guimarães, Agrício Nubiato Crespo, Carlos Takahiro Chone, Eliane M.I. Amstalden   +6 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Suppression of vascular endothelial growth factor expression by cannabinoids in a canine osteosarcoma cell line

Veterinary Medicine: Research and Reports, 2013
Andreza S Figueiredo,1 Hiram J García-Crescioni,1 Sandra C Bulla,1 Matthew K Ross,2 Chelsea McIntosh,1 Kari Lunsford,3 Camilo Bulla11Department of Pathobiology and Population Medicine, 2Department of Basic Sciences, 3Department of Clinical ...
Figueiredo AS, García-Crescioni HJ, Bulla SC, Ross MK, McIntosh C, Lunsford K, Bulla C   +6 more
doaj  

Vascular endothelial growth factor C promotes survival of retinal vascular endothelial cells via vascular endothelial growth factor receptor-2 [PDF]

British Journal of Ophthalmology, 2006
To determine vascular endothelial growth factor C (VEGF-C) expression in retinal endothelial cells, its antiapoptotic potential and its putative role in diabetic retinopathy.Cultured retinal endothelial cells and pericytes were exposed to tumour necrosis factor (TNF)alpha and VEGF-C expression determined by reverse transcriptase-polymerase chain ...
Bojun, Zhao, Gill, Smith, Jun, Cai, Aihua, Ma, Mike, Boulton   +4 more
openaire   +2 more sources

Anti-angiogenic therapies for the treatment of angiosarcoma: a clinical update [PDF]

, 2017
Summary: Angiosarcomas are rare aggressive endothelial tumours, and are associated with a poor prognosis. Due to their vascular nature, there is great interest in their response to anti-angiogenic agents.
A Alvarado-Miranda, A Kollár, C Léauté-Labrèze, CR Antonescu, D Belotti, E Itakura, E Pasquier, H Wong, I Ray-Coquard, IL Ray-Coquard, JM Stiles, L Jonker, LS Rosen, M Agulnik, N Penel, N Penel, O Mir, O Mir, Penella J. Woll, RG Maki, RJ Young, RJ Young, RJ Young, Robin J. Young, S Attia, S Behjati, S Sleijfer, S Zhou, V Raina, W Penella, WD Tap, WT Graaf van der   +31 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Intraocular and systemic levels of vascular endothelial growth factor in advanced cases of retinopathy of prematurity

Clinical Ophthalmology, 2010
Raul Velez-Montoya1, Carmen Clapp2, Jose Carlos Rivera2, Gerardo Garcia-Aguirre1, Virgilio Morales-Cantón1, Jans Fromow-Guerra1, Jose Luis Guerrero-Naranjo1, Hugo Quiroz-Mercado31Retina Department Asociación para Evitar la Ceguera ...
Raul Velez-Montoya, Carmen Clapp, Jose Carlos Rivera, et al   +3 more
doaj  

Anti-VEGF drugs compared with laser photocoagulation for the treatment of diabetic retinopathy: a systematic review and meta-analysis

Health Technology Assessment
Background Diabetic retinopathy is a major cause of sight loss in people with diabetes. The most severe form, proliferative diabetic retinopathy, carries a high risk of vision loss, vitreous haemorrhage, macular oedema and other harms.
Mark Simmonds, Alexis Llewellyn, Ruth Walker, Helen Fulbright, Matthew Walton, Rob Hodgson, Laura Bojke, Lesley Stewart, Sofia Dias, Thomas Rush, John G Lawrenson, Tunde Peto, David Steel   +12 more
doaj   +1 more source

Serum vascular endothelial growth factor levels and tumor molecular marker expression in patients with secondary-edematous breast cancer during treatment dynamics

Journal of V. N. Karazin Kharkiv National University: Series Medicine
Background. Secondary-edematous breast cancer is characterized by high aggressiveness and a lack of clear prognostic markers. Studying the role of Vascular Endothelial Growth Factor in relation to the expression of steroid hormone receptors, HER2/neu ...
O.M. Bilyі, N.A. Mitrіaіeva, L.V. Grebinyk, O.V. Slobodianiuk, S.O. Pylypenko   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source