Results 51 to 60 of about 724,253 (297)

Deleted in Malignant Brain Tumors 1 is Present in the Vascular Extracellular Matrix and Promotes Angiogenesis [PDF]

, 2012
Objective— Deleted in malignant brain tumors 1 (DMBT1) belongs to the scavenger receptor cysteine-rich superfamily of proteins and is implicated in innate immunity, cell polarity, and differentiation.
Eble, Johannes A, Fisslthaler, Beate, Fleming, Ingrid, Hu, Jiong, Mollenhauer, Jan, Müller-Decker, Karin, Müller-Enbergs, Helmut, Popp, Rüdiger, Schmidt, Henrik   +8 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Angiogenic and Neurotrophic Effects of Human Bone Marrow Mesenchymal Stem Cell-Derived Conditioned Medium for Erectile Dysfunction [PDF]

, 2020
Department of Biomedical EngineeringA three-dimensional spheroid culture system to harvest conditioned medium (CM) from human bone marrow-derived mesenchymal stem cells (hBM-MSCs) with high efficiency were introduced and investigated the therapeutic ...
Kim, Seul Gi
core  

VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions [PDF]

, 2014
Vascular endothelial growth factor A (VEGF-A) regulates many aspects of vascular physiology. VEGF-A stimulates signal transduction pathways that modulate endothelial outputs such as cell migration, proliferation, tubulogenesis, and cell-cell interactions.
Abid MR, Abid MR, Adam F. Odell, Alexander F. Bruns, Antony M. Latham, Arthur JS, Baker M, Bartoli M, Bates DO, Bruns AF, Bruns AF, Butler JM, Carl-Henrik Heldin, Carmeliet P, Chen TT, Chung AS, Collins T, Cuhlmann S, Dejana E, Delcombel R, Ding BS, Ewan LC, Fearnley GW, Gareth W. Fearnley, Gerits N, Goddard LM, Griffioen AW, Harper SJ, Herve MA, Holmqvist K, Hordijk PL, Horowitz A, Howell GJ, Ian C. Zachary, Jain RK, Jopling HM, Jopling HM, Karihaloo A, Kawasaki H, Kawasaki H, Keyt BA, Kim I, Kim I, Koch S, Koch S, Lau E, Lemmon MA, Liu D, Meadows KL, Melder RJ, Monica C. Hollstein, Nadeem A. Mughal, Nakatsu MN, Nakayama M, Naldini A, Nicholas J. Burgoyne, Nourshargh S, Pan Q, Panne D, Plotnikov A, Reglero-Real N, Reimold AM, Rivera CG, Salameh A, Schweighofer B, Seko Y, Shalaby F, Shervanthi Homer-Vanniasinkam, Sixt M, Sreenivasan Ponnambalam, Stannard AK, Stephen B. Wheatcroft, Takahashi T, Testori J, Usui T, Weber C, Xu D, Zhang HT, Zhang Y   +78 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Vascular endothelial growth factor inhibitors: investigational therapies for the treatment of psoriasis

Clinical, Cosmetic and Investigational Dermatology, 2013
Anja K Weidemann,1 Ania A Crawshaw,2 Emily Byrne,3 Helen S Young1 1The Dermatology Centre, Salford Royal NHS Foundation Trust, The University of Manchester, Manchester, UK; 2Royal Sussex County Hospital, Brighton, UK; 3University Hospital of South ...
Weidemann AK, Crawshaw AA, Byrne E, Young HS   +3 more
doaj  

Vascular Endothelial Growth Factor Induces Heparin-binding Epidermal Growth Factor-like Growth Factor in Vascular Endothelial Cells [PDF]

Journal of Biological Chemistry, 1998
Although several cytokines and growth factors have been shown to regulate vascular endothelial growth factor (VEGF) production, little is known about how VEGF may regulate growth factors that have known mitogenic and chemotactic actions on mesenchymal cells (which are involved in the maturation of the angiogenic process).
B M, Arkonac, L C, Foster, N E, Sibinga, C, Patterson, K, Lai, J C, Tsai, M E, Lee, M A, Perrella, E, Haber   +8 more
openaire   +2 more sources

Rapamycin Inhibits Proliferation of Hemangioma Endothelial Cells by Reducing HIF-1-Dependent Expression of VEGF [PDF]

, 2012
Hemangiomas are tumors formed by hyper-proliferation of vascular endothelial cells. This is caused by elevated vascular endothelial growth factor (VEGF) signaling through VEGF receptor 2 (VEGFR2).
Medici, Damian, Olsen, Bjorn Reino
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Correlation between vascular endothelial growth factor and nonperfused areas in macular edema secondary to branch retinal vein occlusion

Clinical Ophthalmology, 2013
Masato Fujikawa, Osamu Sawada, Taichiro Miyake, Masashi Kakinoki, Tomoko Sawada, Hajime Kawamura, Masahito Ohji Department of Ophthalmology, Shiga University of Medical Science, Otsu, Japan Purpose: To determine the role of vascular endothelial growth ...
Fujikawa M, Sawada O, Miyake T, Kakinoki M, Sawada T, Kawamura H, Ohji M   +6 more
doaj