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Vascular Endothelial Growth Factor A in Intraocular Vascular Disease
Ophthalmology, 2013The vascular beds supplying the retina may sustain injury as a result of underlying disease such as diabetes, and/or the interaction of genetic predisposition, environmental insults, and age. The vascular pathologic features observed in different intraocular vascular diseases can be categorized broadly as proliferation, exemplified by proliferative ...
Jennifer Le Couter +3 more
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Hypertension and Vascular Endothelial Growth Factors
2015The members of vascular endothelial growth factors (VEGF) are the principal regulators of angiogenesis and vascular biology. The specific growth factor of the endothelial cells is VEGF, which produces nitric oxide (NO) from endothelial cells causing vasodilation.
Luizon, Marcelo Rizzatti +1 more
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Fertility and Sterility, 2008
To investigate how levels of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) change during corpus luteum formation in reproductive aging.Adult and reproductive aging female rats were given pregnant mare serum gonadotropin (PMSG) and the ovaries and sera were collected at 0, 3, 5, and 7 days after human chorionic gonadotropin (hCG ...
Jennifer Peresie, John Yeh, Beom Su Kim
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To investigate how levels of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) change during corpus luteum formation in reproductive aging.Adult and reproductive aging female rats were given pregnant mare serum gonadotropin (PMSG) and the ovaries and sera were collected at 0, 3, 5, and 7 days after human chorionic gonadotropin (hCG ...
Jennifer Peresie, John Yeh, Beom Su Kim
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Regulation of vascular permeability by vascular endothelial growth factors
Vascular Pharmacology, 2002Increased vascular permeability is one of the first stages in both physiological and pathological angiogenesis-the generation of new blood vessels from preexisting vasculature. Although this has been hypothesised to be true in physiological angiogenesis, it is clearly a mark of blood vessel growth in disease.
Steve J Harper, David O. Bates
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Vascular endothelial growth factors in cardiovascular medicine
Journal of Cardiovascular Medicine, 2008The discovery of vascular endothelial growth factors (VEGFs) and their receptors has considerably improved the understanding of the development and function of endothelial cells. Each member of the VEGF family appears to have a specific function: VEGF-A induces angiogenesis (i.e.
Ugo Testa +2 more
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Vascular endothelial growth factor in reproductive biology
Current Opinion in Obstetrics and Gynaecology, 1999The critical role of angiogenesis in embryology and tumor biology has been recognized for more than 20 years. However, the fact that neovascularization is essential to processes in mammalian female reproduction has only recently been appreciated widely. In this review we focus on a single angiogenic growth factor, vascular endothelial growth factor. As
Dan I. Lebovic +2 more
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Inhibitors of Vascular Endothelial Growth Factor in Cancer
Cardiovascular & Hematological Agents in Medicinal Chemistry, 2008Angiogenesis is a complex process that is regulated by pro- and antiangiogenic factors. These factors can emanate from diverse sources including cancer cells, stromal cells, blood and extracellular matrix. Their relative contribution is likely to change with tumor type and tumor site.
Mohammad H. Pourgholami, David L. Morris
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RPE and the Vascular Endothelial Growth Factor [PDF]
, 2020 Vascular endothelial growth factor (VEGF) is a major pro-angiogenic cytokine, but also exerts many additional physiological functions in the retina. The retinal pigment epithelium (RPE) is a major source for VEGF in the retina, especially affecting the endothelium of choriocapillaris but also photoreceptors and the RPE itself. VEGF is regulated on many
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Critical Care Medicine, 2005
Vascular endothelial growth factor (VEGF) regulates vascular proliferation and causes vasodilation. In the pulmonary circulation, the vasorelaxing effect of VEGF has been attributed to nitric oxide, whereas in other vascular beds, prostacyclin and other mechanisms are also involved. This vascular effect follows binding to two receptors, VEGF receptor 1
Sophie Nadeau +3 more
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Vascular endothelial growth factor (VEGF) regulates vascular proliferation and causes vasodilation. In the pulmonary circulation, the vasorelaxing effect of VEGF has been attributed to nitric oxide, whereas in other vascular beds, prostacyclin and other mechanisms are also involved. This vascular effect follows binding to two receptors, VEGF receptor 1
Sophie Nadeau +3 more
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Vascular Endothelial Growth Factor Signaling
2005Vascular endothelial growth factor (VEGF) is the main driving force for angiogenesis and vasculogenesis. Identified as a vascular endothelial cell mitogen and survival factor, it has been sequenced and cloned by Ferrara and Connolly in 1989 [74, 84].
Jean-François Dufour, David Semela
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