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Effects of Finasteride on Vascular Endothelial Growth Factor

Scandinavian Journal of Urology and Nephrology, 2002
Finasteride has been shown to reduce prostate bleeding in patients with benign prostatic hyperplasia (BPH). The mechanisms behind this are not known, but it has been suggested that finasteride reduces bleeding by inhibiting angiogenesis in the prostate. Studies in animals have shown that castration rapidly induces involution of the prostate vasculature,
Häggström, S.   +7 more
openaire   +4 more sources

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor.

Science, 1992
The fms-like tyrosine kinase (Flt) is a transmembrane receptor in the tyrosine kinase family. Expression of flt complementary DNA in COS cells conferred specific, high-affinity binding of vascular endothelial growth factor, also known as vascular ...
C. D. Vries   +5 more
semanticscholar   +1 more source

Hypertension and Vascular Endothelial Growth Factors

2015
The members of vascular endothelial growth factors (VEGF) are the principal regulators of angiogenesis and vascular biology. The specific growth factor of the endothelial cells is VEGF, which produces nitric oxide (NO) from endothelial cells causing vasodilation.
Luizon, Marcelo Rizzatti   +1 more
openaire   +3 more sources

Vascular Endothelial Growth Factor A in Intraocular Vascular Disease

Ophthalmology, 2013
The vascular beds supplying the retina may sustain injury as a result of underlying disease such as diabetes, and/or the interaction of genetic predisposition, environmental insults, and age. The vascular pathologic features observed in different intraocular vascular diseases can be categorized broadly as proliferation, exemplified by proliferative ...
Jennifer Le Couter   +3 more
openaire   +3 more sources

Ovarian vascular endothelial growth factor and vascular endothelial growth factor receptor patterns in reproductive aging

Fertility and Sterility, 2008
To investigate how levels of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) change during corpus luteum formation in reproductive aging.Adult and reproductive aging female rats were given pregnant mare serum gonadotropin (PMSG) and the ovaries and sera were collected at 0, 3, 5, and 7 days after human chorionic gonadotropin (hCG ...
Jennifer Peresie, John Yeh, Beom Su Kim
openaire   +3 more sources

Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy.

Journal of Clinical Oncology, 2002
Vascular endothelial growth factor A (VEGF-A), the founding member of the vascular permeability factor (VPF)/VEGF family of proteins, is an important angiogenic cytokine with critical roles in tumor angiogenesis.
H. Dvorak
semanticscholar   +1 more source

Regulation of vascular permeability by vascular endothelial growth factors

Vascular Pharmacology, 2002
Increased vascular permeability is one of the first stages in both physiological and pathological angiogenesis-the generation of new blood vessels from preexisting vasculature. Although this has been hypothesised to be true in physiological angiogenesis, it is clearly a mark of blood vessel growth in disease.
Steve J Harper, David O. Bates
openaire   +3 more sources

Vascular endothelial growth factors in cardiovascular medicine

Journal of Cardiovascular Medicine, 2008
The discovery of vascular endothelial growth factors (VEGFs) and their receptors has considerably improved the understanding of the development and function of endothelial cells. Each member of the VEGF family appears to have a specific function: VEGF-A induces angiogenesis (i.e.
Ugo Testa   +2 more
openaire   +2 more sources

Biology and therapeutic targeting of vascular endothelial growth factor A

Nature reviews. Molecular cell biology, 2023
Lorena Pérez-Gutiérrez, N. Ferrara
semanticscholar   +1 more source

Vascular endothelial growth factor in reproductive biology

Current Opinion in Obstetrics and Gynaecology, 1999
The critical role of angiogenesis in embryology and tumor biology has been recognized for more than 20 years. However, the fact that neovascularization is essential to processes in mammalian female reproduction has only recently been appreciated widely. In this review we focus on a single angiogenic growth factor, vascular endothelial growth factor. As
Dan I. Lebovic   +2 more
openaire   +3 more sources

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