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Effects of Finasteride on Vascular Endothelial Growth Factor
Scandinavian Journal of Urology and Nephrology, 2002Finasteride has been shown to reduce prostate bleeding in patients with benign prostatic hyperplasia (BPH). The mechanisms behind this are not known, but it has been suggested that finasteride reduces bleeding by inhibiting angiogenesis in the prostate. Studies in animals have shown that castration rapidly induces involution of the prostate vasculature,
Häggström, S.+7 more
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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor.
Science, 1992The fms-like tyrosine kinase (Flt) is a transmembrane receptor in the tyrosine kinase family. Expression of flt complementary DNA in COS cells conferred specific, high-affinity binding of vascular endothelial growth factor, also known as vascular ...
C. D. Vries+5 more
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Hypertension and Vascular Endothelial Growth Factors
2015The members of vascular endothelial growth factors (VEGF) are the principal regulators of angiogenesis and vascular biology. The specific growth factor of the endothelial cells is VEGF, which produces nitric oxide (NO) from endothelial cells causing vasodilation.
Luizon, Marcelo Rizzatti+1 more
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Vascular Endothelial Growth Factor A in Intraocular Vascular Disease
Ophthalmology, 2013The vascular beds supplying the retina may sustain injury as a result of underlying disease such as diabetes, and/or the interaction of genetic predisposition, environmental insults, and age. The vascular pathologic features observed in different intraocular vascular diseases can be categorized broadly as proliferation, exemplified by proliferative ...
Jennifer Le Couter+3 more
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Fertility and Sterility, 2008
To investigate how levels of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) change during corpus luteum formation in reproductive aging.Adult and reproductive aging female rats were given pregnant mare serum gonadotropin (PMSG) and the ovaries and sera were collected at 0, 3, 5, and 7 days after human chorionic gonadotropin (hCG ...
Jennifer Peresie, John Yeh, Beom Su Kim
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To investigate how levels of vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) change during corpus luteum formation in reproductive aging.Adult and reproductive aging female rats were given pregnant mare serum gonadotropin (PMSG) and the ovaries and sera were collected at 0, 3, 5, and 7 days after human chorionic gonadotropin (hCG ...
Jennifer Peresie, John Yeh, Beom Su Kim
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Journal of Clinical Oncology, 2002
Vascular endothelial growth factor A (VEGF-A), the founding member of the vascular permeability factor (VPF)/VEGF family of proteins, is an important angiogenic cytokine with critical roles in tumor angiogenesis.
H. Dvorak
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Vascular endothelial growth factor A (VEGF-A), the founding member of the vascular permeability factor (VPF)/VEGF family of proteins, is an important angiogenic cytokine with critical roles in tumor angiogenesis.
H. Dvorak
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Regulation of vascular permeability by vascular endothelial growth factors
Vascular Pharmacology, 2002Increased vascular permeability is one of the first stages in both physiological and pathological angiogenesis-the generation of new blood vessels from preexisting vasculature. Although this has been hypothesised to be true in physiological angiogenesis, it is clearly a mark of blood vessel growth in disease.
Steve J Harper, David O. Bates
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Vascular endothelial growth factors in cardiovascular medicine
Journal of Cardiovascular Medicine, 2008The discovery of vascular endothelial growth factors (VEGFs) and their receptors has considerably improved the understanding of the development and function of endothelial cells. Each member of the VEGF family appears to have a specific function: VEGF-A induces angiogenesis (i.e.
Ugo Testa+2 more
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Biology and therapeutic targeting of vascular endothelial growth factor A
Nature reviews. Molecular cell biology, 2023Lorena Pérez-Gutiérrez, N. Ferrara
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Vascular endothelial growth factor in reproductive biology
Current Opinion in Obstetrics and Gynaecology, 1999The critical role of angiogenesis in embryology and tumor biology has been recognized for more than 20 years. However, the fact that neovascularization is essential to processes in mammalian female reproduction has only recently been appreciated widely. In this review we focus on a single angiogenic growth factor, vascular endothelial growth factor. As
Dan I. Lebovic+2 more
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