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Molecular and biological properties of the vascular endothelial growth factor family of proteins.
Endocrine reviews, 1992I. Introduction THE establishment of a vascular supply is a critical requirement for cellular inflow of nutrients, outflow of waste products, and gas exchange in most tissues and organs (1).
N. Ferrara +3 more
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Inhibitors of Vascular Endothelial Growth Factor in Cancer
Cardiovascular & Hematological Agents in Medicinal Chemistry, 2008Angiogenesis is a complex process that is regulated by pro- and antiangiogenic factors. These factors can emanate from diverse sources including cancer cells, stromal cells, blood and extracellular matrix. Their relative contribution is likely to change with tumor type and tumor site.
Mohammad H. Pourgholami, David L. Morris
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RPE and the Vascular Endothelial Growth Factor [PDF]
, 2020 Vascular endothelial growth factor (VEGF) is a major pro-angiogenic cytokine, but also exerts many additional physiological functions in the retina. The retinal pigment epithelium (RPE) is a major source for VEGF in the retina, especially affecting the endothelium of choriocapillaris but also photoreceptors and the RPE itself. VEGF is regulated on many
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Vascular endothelial growth factors and angiogenesis.
Annales d'endocrinologie, 2000VEGF was discovered in 1989. Research -conducted over the past 10 years has -demonstrated that VEGF is a major regulator of angiogenesis and vasculogenesis. This paper reviews the molecular data on the multiple forms of VEGF, their signalling and accessory receptors. Five genes encoding VEGF-like proteins have been identified; the different isoforms of
Frelin, C., Ladoux, A., d'Angelo, Gisela
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Vascular endothelial growth factor and POEMS
Neurology, 2006In this issue, Kuwabara et al.1 report on the use of high-dose melphalan and autologous peripheral blood stem cell transplantation (auto-PBSCT, four patients) and high-dose melphalan only (eight patients) in treatment of POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes) syndrome, typical features of which are illustrated ...
Ja Nean K. Engelstad +2 more
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Vascular endothelial growth factor (VEGF) and its receptors
The FASEB Journal, 1999G. Neufeld +3 more
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Vascular Endothelial Growth Factor Signaling
2005Vascular endothelial growth factor (VEGF) is the main driving force for angiogenesis and vasculogenesis. Identified as a vascular endothelial cell mitogen and survival factor, it has been sequenced and cloned by Ferrara and Connolly in 1989 [74, 84].
Jean-François Dufour, David Semela
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Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
Nature, 1992D. Shweiki +3 more
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