Results 141 to 150 of about 28,223,317 (305)

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

Advanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen, Tuba Marjan, Xinyue Lu, Nicole E. Mertens, Keira Vesy, Dean E. Stornello, James F. Markworth, Taimoor H. Qazi   +7 more
wiley   +1 more source

Serum Vascular Endothelial Growth Factor C as a Marker of Therapeutic Response to Sirolimus in Lymphangioleiomyomatosis. [PDF]

Ann Am Thorac Soc, 2021
Gupta N, Hagner M, Wu H, Young LR, Palipana A, Szczesniak RD, McCormack FX.   +6 more
europepmc   +1 more source

Expression of vascular endothelial growth factor-A and vascular endothelial growth factor-C as prognostic factors for non-small cell lung cancer.

Medical science monitor : international medical journal of experimental and clinical research, 2004
Understanding and controlling angiogenesis and lymphangiogenesis could lead to effective strategies for cancer treatment. The aim of our study was to clarify the clinical value of vascular endothelial growth factor-A (VEGF-A) and VEGF-C in non-small cell lung cancer (NSCLC).One hundred and fifty-three patients with NSCLCs were studied to investigate ...
Takashi, Nakashima, Cheng-long, Huang, Dage, Liu, Kotaro, Kameyama, Daiki, Masuya, Masaki, Ueno, Reiji, Haba, Hiroyasu, Yokomise   +7 more
openaire   +1 more source

Growth Differentiation Factor 6 Promotes Vascular Stability by Restraining Vascular Endothelial Growth Factor Signaling

, 2018
The assembly of a functional vascular system requires a coordinated and dynamic transition from activation to maturation. High vascular endothelial growth factor activity promotes activation, including junction destabilization and cell motility ...
Chase H. Melick, Stratman, Amber N.,, Weinstein, Brant M.,, Matteo Malinverno, Jamie Gleklen, R. V. Stan, Melick, Chase H.,, Dejana, Elisabetta,, Radu V. Stan, Amber N. Stratman, J. Gleklen, Gleklen, Jamie,, Krispin, Shlomo,, B. M. Weinstein, Malinverno, Matteo,, S. Krispin, M. Malinverno, Brant M. Weinstein, C. H. Melick, A. N. Stratman, Daniel Castranova, Shlomo Krispin, D. Castranova, Castranova, Daniel,, E. Dejana, Elisabetta Dejana, Stan, Radu V.,   +26 more
core   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Vascular endothelial growth factor-C modulates cortical NMDA receptor activity in cortical lesions of young patients and rat model with focal cortical dysplasia. [PDF]

Brain Pathol, 2022
Shen KF, Duan QT, Duan W, Xu SL, An N, Ke YY, Wang LT, Liu SY, Yang H, Zhang CQ.   +9 more
europepmc   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

Vascular endothelial cells and angiogenesis

Pharmacological Research
Physiological vascular endothelial cell division and angiogenesis occur during embryonic development, wound healing, in the endometrium during the menstrual cycle, and during placental development.
Robert Roskoski, Jr.
doaj   +1 more source

Expression of Vascular Endothelial Growth Factor-C in the Trabecular Meshwork of Patients with Neovascular Glaucoma and Primary Open-Angle Glaucoma. [PDF]

J Clin Med, 2021
Hase K, Kase S, Kanda A, Shinmei Y, Noda K, Ishida S.   +5 more
europepmc   +1 more source

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source