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Vascular Endothelial Growth Factor-C A Growth Factor for Lymphatic and Blood Vascular Endothelial Cells

Trends in Cardiovascular Medicine, 1998
The endothelial cells lining all vessels of the circulatory system have been recognized as key players in a variety of physiological and pathological settings. They act as regulators of vascular tone via the inducible nitric oxide system and in angiogenesis, the formation of blood vessels de novo. Aberrant regulation of endothelial cells contributes to
B, Enholm   +3 more
openaire   +2 more sources

Vascular endothelial growth factors VEGF‐B and VEGF‐C

Journal of Cellular Physiology, 1997
Vascular endothelial growth factor, which was idenheart cDNA library, respectively, by using a serendipitously found partial mouse cDNA clone as a probe tified almost 10 years ago, has so far been considered as the only growth factor relatively specific for endothelial (20,24).
V, Joukov   +7 more
openaire   +2 more sources

Expression of Vascular Endothelial Growth Factor C and Vascular Endothelial Growth Factor Receptor 3 in Corneal Lymphangiogenesis

Experimental Eye Research, 2001
Lymphangiogenesis has been reported in vascularized corneas. However, the molecular mechanisms of lymphangiogenesis in the cornea are still unclear. Since lymphatic vessels may contribute to a decreased success rate of keratoplasty in vascularized cornea by accelerating antigen recognition and graft rejection, elucidation of the mechanisms of corneal ...
T, Mimura   +5 more
openaire   +2 more sources

Developmental expression of vascular endothelial growth factor receptor 3 and vascular endothelial growth factor C in forebrain

Neuroscience, 2015
Increased understanding of the neurovascular niche suggests that development of the central nervous system (CNS) and its vasculature is coordinated through shared regulatory factors. These include the vascular endothelial growth factor (VEGF) family, reported to promote neuroproliferation and neuroprotection in addition to angiogenesis via its ...
M C, Ward, A M, Cunningham
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Co-regulatory potential of vascular endothelial growth factor–A and vascular endothelial growth factor–C in thyroid carcinoma

Human Pathology, 2013
Vascular endothelial growth factor (VEGF) promotes growth of blood or lymphatic vessels. The aim of the current study is to identify relationships between VEGF-A and VEGF-C, and their impact in angiogenesis and metastases in thyroid cancers. VEGF-A and VEGF-C mRNA and protein expression was investigated in 136 thyroid cancers (123 papillary thyroid ...
Salajegheh, Ali   +9 more
openaire   +3 more sources

Vascular Endothelial Growth Factor Suppresses C-Type Natriuretic Peptide Secretion

Hypertension, 1996
Abstract Angiogenesis plays a pivotal role not only in wound healing and tumor progression but also in diabetic angiopathy, arteriosclerosis, and collateral formation of obstructive vascular diseases. Vascular endothelial growth factor (VEGF) is now thought to be an endothelium-specific and potent angiogenic factor.
K, Doi   +9 more
openaire   +2 more sources

Serum vascular endothelial growth factor-C and vascular endothelial growth factor level in patients with colorectal carcinoma and clinical significance

Journal of Huazhong University of Science and Technology [Medical Sciences], 2006
Circulating vascular endothelial growth factor-C (VEGF-C) and vascular endothelial growth factor (VEGF) levels in patients with colorectal carcinoma were determined in order to assess their clinical significance as a diagnostic tool for monitoring lymph node metastasis.
Tianwen, Xu, Daoda, Chen
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Vascular Endothelial Growth Factor–C (VEGF-C) Expression in Normal Human Tissues

Lymphatic Research and Biology, 2006
To characterize vascular endothelial growth factor-C (VEGF-C) protein expression in normal human tissues by immunohistochemistry (IHC). VEGF-C is a growth factor for lymphatic endothelial cells. VEGF-C mRNA and protein are expressed in a variety of cancerous tissues, but the localization of VEGF-C protein in many normal human tissues has not been ...
K D, Joory   +3 more
openaire   +2 more sources

Vascular Endothelial Growth Factor-C and Vascular Endothelial Growth Factor-D mRNA Expression in Breast Cancer: Association with Lymph Node Metastasis

Clinical Breast Cancer, 2003
Lymph node metastasis is a major prognostic factor for patients with breast cancer. Vascular endothelial growth factors (VEGF)-C and VEGF-D are capable of stimulating lymphangiogenesis, and VEGF-C enhances lymphatic metastasis. The aim of the present study was to determine whether VEGF-C and VEGF-D messenger RNA (mRNA) expression is correlated with ...
Yu, Koyama   +5 more
openaire   +2 more sources

Immunodetection and molecular forms of plasma vascular endothelial growth factor-C

International Journal of Oncology, 2003
Vascular endothelial growth factor (VEGF)-C is a member of the VEGF family. VEGF-C is involved in developmental lymphangiogenesis and may be important in pathological lymphangiogenesis, lymphatic invasion and metastasis in carcinoma. We describe the development of an indirect enzyme-linked immunosorbent (ELISA) assay for the quantification of VEGF-C in
S E, Duff   +4 more
openaire   +2 more sources

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