Results 121 to 130 of about 331,972 (306)

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

New derivatives based on zerumbone scaffold as anticancer inhibitors: Synthesis, in vitro anticancer evaluation, docking, and MD simulation studies

Journal of Chemical Research
A three-step procedure was applied to synthesize seven novel zerumbone ethers 7a–g with N -(4-hydroxybenzyl) benzamide, N -(4-hydroxybenzyl) substituted benzamide, and N -(4-hydroxybenzyl) cinnamamide moieties, including simultaneous O - and N ...
Ngoc Hung Truong, Minh Ha Le, Hanh Trang Luu, Tien Chinh Vu, Van Chung Pham, Van Chinh Luu   +5 more
doaj   +1 more source

Neurokinin-1 receptor antagonists as antitumor drugs in gastrointestinal cancer: A new approach

The Saudi Journal of Gastroenterology, 2016
Gastrointestinal (GI) cancer is the term for a group of cancers affecting the digestive system. After binding to the neurokinin-1 (NK-1) receptor, the undecapeptide substance P (SP) regulates GI cancer cell proliferation and migration for invasion and ...
Miguel Muñoz, Rafael Coveñas
doaj   +1 more source

Analysis of the mechanisms of resistance to Epidermal growth factor receptor inhibitors and development of multiple targeted strategies

, 2008
Background. Primary and acquired resistance to selective Epidermal growth factor receptor (EGFR) inhibitors remains the most significant obstacle to the success of these targeted agents in cancer therapy.
Rosa, Roberta
core  

New molecular mediators in tumor angiogenesis

, 2007
Angiogenesis is essential for tumor growth and progression. It has been demonstrated that tumor growth beyond a size 1 to 2 mm3 requires the induction of new vessels.
Jonas, Dietger, Beecken, Wolf-Dietrich, Kramer, Wolfgang   +2 more
core   +1 more source

Targeting tumor vasculature [PDF]

, 2009
Targeting tumor vasculature is the common theme for the three separate studies presented in this thesis. The studies comprise the roles of components of three signaling pathways (networks) in several steps of blood vessel formation, and related tumor ...
Samaržija, Ivana
core   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Serum Soluble Vascular Endothelial Growth Factor Receptor 1 as a Potential Biomarker of Hepatopulmonary Syndrome. [PDF]

J Clin Transl Hepatol, 2023
Li YJ, Wu XF, Wang DD, Li P, Liang H, Hu XY, Gan JQ, Sun YZ, Li JH, Li J, Shu X, Song AL, Yang CY, Yang ZY, Yu WF, Yang LQ, Wang XB, Belguise K, Xia ZY, Xia ZY, Yi B.   +20 more
europepmc   +1 more source

Expression of vascular endothelial growth factor (VEGF) and its soluble receptor-1 in endometriosis

Microvascular Research, 2012
The aim of this study is to evaluate the expression of vascular endothelial growth factor (VEGF) and its soluble receptor (sFlt-1) in peritoneal fluid (PF), peritoneal endometriotic lesions and eutopic endometrial tissues of patients with endometriosis.
SiHyun, Cho, Young Sik, Choi, Young Eun, Jeon, Kyung Jin, Im, Young Mi, Choi, Su Youn, Yim, HyeYeon, Kim, Seok Kyo, Seo, Byung Seok, Lee   +8 more
openaire   +3 more sources

Role of chemerin, a novel adipochemokine, in the human microvascular endothelial cell (HMEC)-1 line [PDF]

Chemerin is a newly identified adipokine and exerts its functional effects by binding to its natural GPCR, known as CMKLR1. Chemerin is highly expressed in the adipose tissue and in lower levels in other body tissues; and is known to play an important
Kaur, Jaspreet
core