Results 131 to 140 of about 331,972 (306)

Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells [PDF]

, 2009
Background Treatment options for metastatic renal cell carcinoma (RCC) are limited due to resistance to chemo- and radiotherapy. The development of small-molecule multikinase inhibitors have now opened novel treatment options.
Natsheh, Iyad Y. M., Eva Juengel, Mickuckyte, Ausra, Hudak, Lukasz, Jones, Jon, Roman A Blaheta, Lukasz Hudak, Jüngel, Eva, Dietger Jonas, Blaheta, Roman A., Johanna Engler, Iyad Natsheh, Ausra Mickuckyte, Jonas, Dietger, Jon Jones, Engler, Johanna   +15 more
core   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Analysis of results determination of level of vascular endothelial growth factor, receptor for vascular endothelial growth factor and big endotelin-1 in structure of arteriovenous malformations

Українська Інтервенційна Нейрорадіологія та Хірургія, 2022
Objective ‒ to assess the diagnostic significance of angiogenesis factors based on the study of the level of angiogenesis factors (vascular endothelial growth factor (VEGF-A), specific receptor for vascular endothelial growth factor (VEGFR-1 ...
I.V. Altman
doaj  

Vascular endothelial growth factor receptor 1 gene (<i>FLT1</i>) longevity variant increases lifespan by reducing mortality risk posed by hypertension. [PDF]

Aging (Albany NY), 2023
Morris BJ, Chen R, Donlon TA, Kallianpur KJ, Masaki KH, Willcox BJ.   +5 more
europepmc   +1 more source

Exploring the dermal immune and angiogenic responses to Schistosoma mansoni [PDF]

, 2011
Schistosoma mansoni is a parasitic helminth which gains access to the host’s vascular system by penetrating and migrating through the skin in search of a blood vessel.
Aynsley, Sarah Amelia
core  

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

, 2012
Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1
Devraj, Kavi, Nicole Ziegler, Fruttiger, Marcus, Rosario Heck, Sascha Seidel, Sonja Thom, Taketo, Makoto Mark, Kavi Devraj, Seidel, Sascha, Karl H. Plate, Liebner, Stefan, Reis, Marco, Bockamp, Ernesto, Heck, Rosario, Ernesto Bockamp, Marco Reis, Cathrin J. Czupalla, Makoto M. Taketo, Thom, Sonja, Zinke, Jenny, Plate, Karl, Macas, Jadranka, Jenny Zinke, Czupalla, Cathrin Jacqueline, Jadranka Macas, Stefan Liebner, Stefanie Dimmeler, Dimmeler, Stefanie, Ziegler, Nicole, Marcus Fruttiger   +29 more
core   +1 more source

Conductive Hydrogels for Exogenous Sensing and Cell Fate Control

Advanced Materials, EarlyView.
We engineer electrically conductive hydrogels by combining sulfated glycosaminoglycans with semiconducting polymers. These hydrogels bind bioactive proteins, including growth factors, whose release or retention can be modulated by low‐voltage stimulation. The hydrogels are also integrated as 3D channels in organic electrochemical transistors as part of
Teuku Fawzul Akbar, Carlos Alejandro Jimenez‐Rodriguez, Railia Biktimirova, Ilka Hermes, Thomas Kurth, My Duyen Pham, Mikhail Tsurkan, Jens Friedrichs, Francis L. C. Morgan, Hans Kleemann, Olga Guskova, Uwe Freudenberg, Peter Fratzl, Carsten Werner, Christoph Tondera, Ivan R. Minev   +15 more
wiley   +1 more source

Super‐Resolution Ultrasound Based Cell Tracking With Polymeric Nanobubbles

Advanced Materials, EarlyView.
This study presents a super‐resolution ultrasound platform for tracking cells in vivo. Biocompatible polymeric nanobubbles are used as highly echogenic intracellular labels. Following the injection of cells and microbubbles, ultrasound localization microscopy (ULM) can dynamically match the microvascular architecture and individual cell trajectories ...
Junlin Chen, Xiaoyu Wang, Jilin Fan, Bi Wang, Hanghang Fang, Yurui Wang, Hao Cui, Mohammad Roufarshbaf, Ekaterina Savina, Alexandra Valeske, Quim Peña, Yang Shi, Andreas Herrmann, Twan Lammers, Mathias Hornef, Roman Barmin, Thomas Lisson, Georg Schmitz, Anne Rix, Fabian Kiessling   +19 more
wiley   +1 more source

Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis

Pharmacological Research
The osteopontin-derived peptide FOL-005 stimulates hair growth. Using ligand-receptor glyco-capture technology we identified neuropilin-1 (NRP-1), a known co-receptor for vascular endothelial growth factor (VEGF) receptors, as the most probable receptor ...
Yihong Chen, Chrysostomi Gialeli, Junyan Shen, Pontus Dunér, Björn Walse, Annette Duelli, Rhawnie Caing-Carlsson, Anna M. Blom, John R. Zibert, Anna Hultgårdh Nilsson, Jan Alenfall, Chun Liang, Jan Nilsson   +12 more
doaj   +1 more source

Neuro-oncological Ventral Antigen 2 Regulates Splicing of Vascular Endothelial Growth Factor Receptor 1 and Is Required for Endothelial Function. [PDF]

Reprod Sci, 2023
Kremer V, Oppelaar JJ, Gimbel T, Koziarek S, Ganzevoort W, van Pampus MG, van den Born BJ, Vogt L, de Groot C, Boon RA.   +9 more
europepmc   +1 more source