Results 261 to 270 of about 650,658 (370)

NaBC1 Boron Transporter Enables Myoblast Response to Substrate Rigidity via Fibronectin‐Binding Integrins

Advanced Science, EarlyView.
Cells transduce the rigidity of the environment into biochemical cues through mechanotransductive cascades that modulate cell behavior. Here, a novel role for the boron transporter NaBC1 is identified as a mechanotransducer involved in regulating cell behavior via specific crosstalk with fibronectin‐binding integrins.
Juan Gonzalez‐Valdivieso, Giuseppe Ciccone, Udesh Dhawan, Tezz Quon, Eva Barcelona‐Estaje, Aleixandre Rodrigo‐Navarro, Rafael R. Castillo, Graeme Milligan, Patricia Rico, Manuel Salmeron‐Sanchez   +9 more
wiley   +1 more source

Vascular Endothelial Growth Factor Receptor 2 (VEGFR2) rs2071559 Gene Polymorphism and the Risk of Gliomas: A Systematic Review and Meta-Analysis. [PDF]

J Clin Med
Prasetiyo PD, Wahjoepramono EJ.
europepmc   +1 more source

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

Advanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi, Yanxia Wang, Huan Chen, Kaitian Wu, Pei Zhou, Yue Dou, Bingqi Xiong, Wei Zhou   +7 more
wiley   +1 more source

Phase I study of BC001, a novel fully human immunoglobulin G1 monoclonal antibody targeting the vascular endothelial growth factor receptor-2, in advanced solid tumors. [PDF]

Cancer Med
Liu D, Gong J, Liu M, Zhou H, Wang S, Yang J, Shang C, Guo X, Wang C, Zhang Y, Shen L.   +10 more
europepmc   +1 more source

Activation of Vascular Endothelial Growth Factor Receptor-2 in Bone Marrow Leads to Accumulation of Myeloid Cells: Role of Granulocyte-Macrophage Colony-Stimulating Factor [PDF]

, 2005
Bruno Larrivée, Ingrid L. Pollet, Aly Karsan   +2 more
openalex   +1 more source

Bioprinted Patient‐Derived Organoid Arrays Capture Intrinsic and Extrinsic Tumor Features for Advanced Personalized Medicine

Advanced Science, EarlyView.
An embedded bioprinting enabled‐arrayed patient‐derived organoids (Eba‐PDO) platform that replicates intrinsic and extrinsic tumor characteristics is introduced. Eba‐PDOs more accurately mimic tissue than standard PDOs (Std‐PDOs) due to maturation in the tumor microenvironment.
Jonghyeuk Han, Hye‐Jin Jeong, Jeonghan Choi, Hyeonseo Kim, Taejoon Kwon, Kyungjae Myung, Kyemyung Park, Jung In Park, Samuel Sánchez, Deok‐Beom Jung, Chang Sik Yu, In Ho Song, Jin‐Hyung Shim, Seung‐Jae Myung, Hyun‐Wook Kang, Tae‐Eun Park   +15 more
wiley   +1 more source

Endomucin selectively regulates vascular endothelial growth factor receptor-2 endocytosis through its interaction with AP2. [PDF]

Cell Commun Signal
Cano I, Wild M, Gupta U, Chaudhary S, Ng YSE, Saint-Geniez M, D'Amore PA, Hu Z.   +7 more
europepmc   +1 more source

Acquired Expression of Periostin by Human Breast Cancers Promotes Tumor Angiogenesis through Up-Regulation of Vascular Endothelial Growth Factor Receptor 2 Expression

, 2004
Rong Shao, Shideng Bao, Xuefang Bai, Carrie Blanchette, Ryan M. Anderson, Tongyun Dang, Mikhail L. Gishizky, Jeffrey R. Marks, Xiao-Fan Wang   +8 more
openalex   +1 more source

Angiogenesis Inhibition by Vascular Endothelial Growth Factor Receptor-2 Blockade Reduces Stromal Matrix Metalloproteinase Expression, Normalizes Stromal Tissue, and Reverts Epithelial Tumor Phenotype in Surface Heterotransplants [PDF]

, 2005
Silvia Vosseler, Nicolae Mirancea, Peter Böhlen, Margareta M. Mueller, Norbert E. Fusenig   +4 more
openalex   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source