Results 341 to 350 of about 650,658 (370)

Placental Growth Factor and Vascular Endothelial Growth Factor Receptor-2 in Human Lung Development

Pediatrics, 2008
OBJECTIVE. We examined the pulmonary expression of 2 proangiogenic factors, namely, placental growth factor and vascular endothelial growth factor receptor-2, during lung development and acute and chronic lung injury in newborn infants.METHODS. Six groups were included in an immunohistochemical study of placental growth factor and vascular endothelial ...
Patrik Lassus, Caj Haglund, Sture Andersson, Riitta Karikoski, Joakim Janér   +4 more
openaire   +2 more sources

Contribution of vascular endothelial growth factor receptor-2 sialylation to the process of angiogenesis

Oncogene, 2017
Vascular endothelial growth factor receptor-2 (VEGFR2) is the main pro-angiogenic receptor expressed by endothelial cells (ECs). Using surface plasmon resonance, immunoprecipitation, enzymatic digestion, immunofluorescence and cross-linking experiments with specific sugar-binding lectins, we demonstrated that VEGFR2 bears both α,1-fucose and α(2,6 ...
CHIODELLI, Paola, REZZOLA, Sara, URBINATI, Chiara Eva, FEDERICI SIGNORI, FEDERICA, MONTI, Eugenio, RONCA, Roberto, PRESTA, Marco, RUSNATI, Marco   +7 more
openaire   +4 more sources

Diagnostic and Prognostic Performance of Serum Vascular Endothelial Growth Factor, Vascular Endothelial Growth Factor Receptor 2, and Osteopontin for Gastrointestinal Cancers

Clinical Laboratory, 2019
Biomarkers for early diagnosis and follow-up of cancers are still underutilized in clinical management. Thus, seeking new biomarkers with better sensitivity and specificity is still a challenge. VEGF, VEGFR2, and OPN are newly emerging biomarkers with clinical potential.ELISA was used to analyze serum VEGF, VEGFR2, and OPN from 75 gastrointestinal ...
Yanyun Chen, Qiulian Zhong, Liejun Jiang, Tan Chunyan, Shuang Deng, Steven N. Hochwald, Huayi Huang   +6 more
openaire   +2 more sources

Vascular endothelial growth factor receptor-2 inhibition in experimental murine colitis

Journal of Surgical Research, 2013
In the setting of inflammatory bowel disease, inflammation is associated with a simultaneous increase in angiogenesis; moreover, elevated vascular endothelial growth factor (VEGF) levels implicate angiogenesis as a pathologic contributor to disease severity.
Mary R. Dusing, Artur Chernoguz, E.C. Donovan, Kelly M. Crawford, Jason S. Frischer, Leslie Knod   +5 more
openaire   +3 more sources

Expression and Significance of Vascular Endothelial Growth Factor Receptor 2 in Bladder Cancer

Journal of Urology, 2006
Vascular endothelial growth factor has a critical role in maintaining tumor microvasculature and, as such, is an attractive target for anti-angiogenic therapy. Aberrant expression of VEGF receptors, especially VEGFR2, on epithelial tumor cells allows VEGF to stimulate growth and migration of tumor cells in an autocrine and/or paracrine manner ...
Susan Groshen, David I. Quinn, Daniel Broek, Sutao Zhu, John P. Stein, Jie Cai, Debra Hawes, S. Ram Kumar, Parkash S. Gill, Rizwan Masood, Loubna Hassanieh, Guangbin Xia   +11 more
openaire   +3 more sources

Expression of Peroxiredoxin 2 and Vascular Endothelial Growth Factor Receptor 2 in Pterygium

Cornea, 2017
Purpose: The expression of peroxiredoxin 2 and vascular endothelial growth factor receptor 2 (VEGFR2) was detected in pterygium to investigate whether they are involved in the pathogenesis or recurrence of pterygium and to evaluate the association between peroxiredoxin 2 and VEGFR2 in pterygium.
Peng Hao, Jinyong Lin, Xuan Li, Luxia Chen, Liming Wang, Yuchuan Wang, Ming Ying, Ruifang Han   +7 more
openaire   +3 more sources

Expression and localization of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 in human epidermal appendages: a comparison study by immunofluorescence

Clinical and Experimental Dermatology, 2009
Vascular endothelial growth factor (VEGF) promotes angiogenesis and plays important roles in neovascularization and development of tissues. VEGF receptors (VEGFRs) are high-affinity receptors for VEGF and are originally considered specific to endothelial cells. We have previously shown that keratinocytes from human normal skin express VEGFRs.
Zhong-Fa Lu, Sui-Qing Cai, Zhang-Yu Bu, Xiao-Yong Man, Xiao-Hong Yang, Min Zheng, Xian-Jie Wu   +6 more
openaire   +3 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel, William K Oh, Matthew D Galsky   +2 more
exaly