Unjamming and nematic flocks in endothelial monolayers during angiogenesis : theoretical and experimental analysis [PDF]
, 2018 Angiogenesis is the complex process by which new blood vessels develop from an existing vasculature in order to supply nutrients and/or metabolites to tissues, playing a fundamental role in many physiological and pathological conditions such as embryogenesis and tissue repair or tumour growth.
arxiv +1 more source
Mathematical modeling of glioma invasion and therapy approaches via kinetic theory of active particles [PDF]
arXiv, 2022 A multiscale model for glioma spread in brain tissue under the influence of vascularization and vascular endothelial growth factors is proposed. It accounts for the interplay between the different components of the neoplasm and the healthy tissue and it investigates and compares various therapy approaches.
arxiv
Role of vascular endothelial growth factor and other growth factors in post-stroke recovery
Annals of Indian Academy of Neurology, 2014 Stroke is a major health problem world-wide and its burden has been rising in last few decades. Until now tissue plasminogen activator is only approved treatment for stroke.
Tanu Talwar +1 more
doaj +1 more source
Transcriptional profiling reveals fundamental differences in iPS-derived progenitors of endothelial cells (PECs) versus adult circulating EPCs [PDF]
arXiv, 2020 There are a number of different stem cell sources that have the potential to be used as therapeutics in vascular degenerative diseases. On the one hand, there are so called endothelial progenitor cells (EPCs), which are typically derived from adult blood. They carry the marker CD34, but the true nature and definition of EPCs is still controversial.
arxiv
Shared features of endothelial dysfunction between sepsis and its preceding risk factors (aging and chronic disease) [PDF]
, 2018 Acute vascular endothelial dysfunction is a central event in the pathogenesis of sepsis,increasing vascular permeability, promoting activation of the coagulation cascade, tissue edema and compromising perfusion of vital organs. Aging and chronic diseases(hypertension,dyslipidaemia,diabetes mellitus,chronic kidney disease,cardiovascular disease ...
arxiv +1 more source
The function of vascular endothelial growth factor
BioFactors, 2009 AbstractVascular endothelial growth factor (VEGF) is considered the master regulator of angiogenesis during growth and development, as well as in disease states such as cancer, diabetes, and macular degeneration. This review details our current understanding of VEGF signaling and discusses the benefits and unexpected side effects of promising anti ...
Bonnie J. Nieves +2 more
openaire +4 more sources
Advanced Science, 2019 Placental vasculopathies are associated with a number of pregnancy‐related diseases, including pre‐eclampsia (PE)—a leading cause of maternal–fetal morbidity and mortality worldwide.
Kristina Haase +3 more
doaj +1 more source
Aortic dissection induced by vascular endothelial growth factor inhibitors
Frontiers in Pharmacology, 2023 Vascular endothelial growth factor (VEGF) contributes to angiogenesis and vasculogenesis. The occurrence and progression of tumors are accompanied by angiogenesis.
Shuqi Dai +4 more
doaj +1 more source
Vascular Endothelial Growth Factor Induces Heparin-binding Epidermal Growth Factor-like Growth Factor in Vascular Endothelial Cells [PDF]
Journal of Biological Chemistry, 1998 Although several cytokines and growth factors have been shown to regulate vascular endothelial growth factor (VEGF) production, little is known about how VEGF may regulate growth factors that have known mitogenic and chemotactic actions on mesenchymal cells (which are involved in the maturation of the angiogenic process).
Jer-Chia Tsai +9 more
openaire +3 more sources
São Paulo Medical JournalBACKGROUND: Increased angiogenetic activity in inflammatory bowel disease (IBD) has been shown in previous studies. The aim of this study was to evaluate the relationship of serum vascular endothelial growth factor (VEGF) and endostatin levels with ...
Evrim Kahramanoğlu Aksoy +5 more
doaj +1 more source