Comparison of Continuous and Periodic Exercise on Serum Nitric Oxide Level and Vascular Endothelial Growth Factor in Old Rats [PDF]
Background and objectives: Considering the importance of aging and the associated physiological changes, as well as the effects of exercise on angiogenesis and cardiac index, this study aimed to compare continuous and periodic exercise in form of high ...
Abdolhamid Zokaei +3 more
doaj
Updates on Anticancer Therapy-Mediated Vascular Toxicity and New Horizons in Therapeutic Strategies
Vascular toxicity is a frequent adverse effect of current anticancer chemotherapies and often results from endothelial dysfunction. Vascular endothelial growth factor inhibitors (VEGFi), anthracyclines, plant alkaloids, alkylating agents, antimetabolites,
Po-Yen Hsu +4 more
doaj +1 more source
Dementia is one of the most disabling non-motor symptoms in Parkinson’s disease (PD). Unlike in Alzheimer’s disease, the vascular pathology in PD is less documented.
Anna Pierzchlińska +4 more
doaj +1 more source
Differentiation of the brain vasculature : the answer came blowing by the Wnt [PDF]
Vascularization of the vertebrate brain takes place during embryonic development from a preformed perineural vascular plexus. As a consequence of the intimate contact with neuroectodermal cells the vessels, which are entering the brain exclusively via ...
Liebner, Stefan +3 more
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Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression [PDF]
Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1
Devraj, Kavi +29 more
core +1 more source
Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature [PDF]
Vascular endothelial growth factor (VEGF) plays a critical role in normal development as well as retinal vasculature disease. During retinal vascularization, VEGF is most strongly expressed by not yet vascularized retinal astrocytes, but also by retinal ...
Michael B. Powner +43 more
core +3 more sources
THE ROLE OF DYSLIPIDEMIA IN THE PROGRESSION OF DIABETIC RETINOPATHY
Angiogenesis factors, growth factors (vascular endothelial growth factor (VEGF), angiopoietin-2, insulin-like growth factor, etc.) and cytokines play the leading role in the production by endothelial cells of new retinal blood vessels, increased vascular
A. G. Kuzmin +2 more
doaj +1 more source
Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Losa, Marco +16 more
core +1 more source
Vasculogenesis, angiogenesis and arteriogenesis represent three crucial mechanisms involved in the formation and maintenance of the vascular network in embryonal and post-natal life. It has long been known that endothelial Ca2+ signals are key players in
Sharon Negri +4 more
doaj +1 more source
Vascular function and cardiovascular risk factors in women with severe flushing [PDF]
Background: Seventy per cent of postmenopausal women suffer from hot flushes causing significant morbidity in 25%. Oestrogen replacement provides symptom relief, but its use has declined following safety issues and there is, as yet, no good alternative ...
J. Sassarini +9 more
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