Results 21 to 30 of about 12,742,672 (289)

Vascular endothelial growth factors and vascular permeability [PDF]

Cardiovascular Research, 2010
Vascular endothelial growth factors (VEGFs) are key regulators of permeability. The principal evidence behind how they increase vascular permeability in vivo and in vitro and the consequences of that increase are addressed here. Detailed analysis of the published literature has shown that in vivo and in vitro VEGF-mediated permeability differs in its ...
openaire   +2 more sources

The biology of vascular endothelial growth factors [PDF]

Cardiovascular Research, 2005
The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has provided tools for studying the vascular system in development as well as in diseases ranging from ischemic heart disease to cancer.
Tuomas, Tammela, Berndt, Enholm, Kari, Alitalo, Karri, Paavonen   +3 more
openaire   +2 more sources

VASCULAR ENDOTHELIAL GROWTH FACTORS IN HEART TRANSPLANT REJECTIONS

Вестник трансплантологии и искусственных органов, 2015
Aim: to determine the clinical significance of vascular endothelial growth factors VEGF-A, VEGF-D, PlGF-1 to assess the risk of cardiovascular complications in heart recipients. Materials and methods.
O. P. Shevchenko, E. A. Stakhanova, A. O. Shevchenko, N. P. Mogeiko, O. E. Gichkun   +4 more
doaj   +1 more source

Vasoregulatory Autoantibodies and Clinical Outcome After Ischemic Stroke—PROSCIS‐B

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Vasoregulatory autoantibodies including autoantibodies targeting G‐protein–coupled receptors might play a functional role in vascular diseases.
Thomas G. Liman, Bob Siegerink, Sophie Piper, Rusan Catar, Guido Moll, Gabriela Riemekasten, Harald Heidecke, Peter U. Heuschmann, Mitchell S. V. Elkind, Duska Dragun, Matthias Endres   +10 more
doaj   +1 more source

Vascular endothelial growth factor-tyrosine kinase inhibitors: Novel mechanisms, predictors of hypertension and management strategies

American Heart Journal Plus, 2022
Vascular endothelial growth factor inhibition has become a cornerstone of cancer therapy. Significant adverse effect is associated with these therapies, with hypertension among the most prevalent.
Javier A. Gomez
doaj   +1 more source

Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders

Pharmaceuticals, 2023
Vascular endothelial growth factors (VEGFs) are key mediator of retinal and choroidal neovascularization as well as retinal vascular leakage leading to macular edema.
Abraham Hang, Samuel Feldman, Aana P. Amin, Jorge A. Rivas Ochoa, Susanna S. Park   +4 more
doaj   +1 more source

VEGF guides angiogenic sprouting utilizing endothelial tip cell filopodia [PDF]

, 2003
Vascular endothelial growth factor (VEGF-A) is a major regulator of blood vessel formation and function. it controls several processes in endothelial cells, such as proliferation, survival, and migration, but it is not known how these are coordinately ...
Shima, D., Christiana Ruhrberg, Betsholtz, C, Jeltsch, M, Abramsson, A., Shima, D, Matthew Golding, Lundkvist, A, Lundkvist, A., Golding, M, David Shima, Ruhrberg, C, Christopher Mitchell, Mitchell, C, Betsholtz, C., Kari Alitalo, Gerhardt, H, Ruhrberg, C., Christer Betsholtz, Golding, M., Jeltsch, M., Holger Gerhardt, Abramsson, A, Alitalo, K, Andrea Lundkvist, Fruttiger, M., Gerhardt, H., Alitalo, K., Alexandra Abramsson, Mitchell, C., Fruttiger, M, Michael Jeltsch, Marcus Fruttiger   +32 more
core   +1 more source

Updates on Anticancer Therapy-Mediated Vascular Toxicity and New Horizons in Therapeutic Strategies

Frontiers in Cardiovascular Medicine, 2021
Vascular toxicity is a frequent adverse effect of current anticancer chemotherapies and often results from endothelial dysfunction. Vascular endothelial growth factor inhibitors (VEGFi), anthracyclines, plant alkaloids, alkylating agents, antimetabolites,
Po-Yen Hsu, Aynura Mammadova, Nadia Benkirane-Jessel, Laurent Désaubry, Canan G. Nebigil   +4 more
doaj   +1 more source

Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]

, 2001
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Losa, Marco, Lohrer, P., Gloddek, J., Renner, U., Lohrer, Penny, Uhl, E., Stalla, G., Pagotto, U., Hopfner, Ursula, Renner, Ulrich, Losa, Marc, Losa, M., Pagotto, Uberto, Gloddek, Jutta, Uhl, Eberhard, Stalla, Günter K., Hopfner, U.   +16 more
core   +1 more source

Arterial Blood Pressure Variability and Other Vascular Factors Contribution to the Cognitive Decline in Parkinson’s Disease

Molecules, 2021
Dementia is one of the most disabling non-motor symptoms in Parkinson’s disease (PD). Unlike in Alzheimer’s disease, the vascular pathology in PD is less documented.
Anna Pierzchlińska, Magdalena Kwaśniak-Butowska, Jarosław Sławek, Marek Droździk, Monika Białecka   +4 more
doaj   +1 more source