Results 41 to 50 of about 840,839 (338)

Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders

Pharmaceuticals, 2023
Vascular endothelial growth factors (VEGFs) are key mediator of retinal and choroidal neovascularization as well as retinal vascular leakage leading to macular edema.
Abraham Hang, Samuel Feldman, Aana P. Amin, Jorge A. Rivas Ochoa, Susanna S. Park   +4 more
doaj   +1 more source

Updates on Anticancer Therapy-Mediated Vascular Toxicity and New Horizons in Therapeutic Strategies

Frontiers in Cardiovascular Medicine, 2021
Vascular toxicity is a frequent adverse effect of current anticancer chemotherapies and often results from endothelial dysfunction. Vascular endothelial growth factor inhibitors (VEGFi), anthracyclines, plant alkaloids, alkylating agents, antimetabolites,
Po-Yen Hsu, Aynura Mammadova, Nadia Benkirane-Jessel, Laurent Désaubry, Canan G. Nebigil   +4 more
doaj   +1 more source

Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. [PDF]

, 2005
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans ...
Aigner, Arany, Asplin, Auguste, Baird, Baird, Barleon, Bastaki, Bergonzoni, Bikfalvi, Birkle, Blotnick, Bornstein, Bossard, Bottazzi, Breviario, Brown, Brustle, Cao, Cao, Carmeliet, Carmeliet, Carmeliet, Castellon, Chadderton, Chang, Chang, Chang, Chi, Collo, Coltrini, Colvin, Comerota, Compagni, Conforti, Connolly, Costa, Cozzolino, Cross, Czubayko, Daviet, Davis, De Marchis, Dell’Era, Dell’Era, Dell’Era, Deng, Dennis, Desbaillets, Dirix, Eliceiri, Ensoli, Eriksson, Ferrara, Ferrara, Florkiewicz, Folkman, Folkman, Folkman, Freedman, Fulgham, Gabler, Gajdusek, Gajdusek, Garlanda, Gerritsen, Giavazzi, Giavazzi, Gillis, Giordano, Gleich, Gloe, Gonzalez, Griffioen, Grines, Gross, Gualandris, Gualandris, Hanahan, Hanneken, Hanneken, Hartnett, Henke, Herbert, Hiraoka, Ho, Hollingsworth, Hori, Hoying, Hsia, Iozzo, Itoh, Jaakkola, Javerzat, Jih, Kage, Kanda, Kanda, Kandel, Kaneko, Kasahara, Kazemi, Kitayama, Kiuru-Kuhlefelt, Klein, Konerding, Konkle, Koochekpour, Kumar, Kumar, Kumar, Kurz, Kuwabara, Laham, Landgren, Latini, Lazarous, Leali, Lederman, Lee, Lee, Li, Li, Lindahl, Liotta, Lopez, Lozano, Maciag, Magnusson, Mantovani, Margosio, Mathew, Matsumoto, Mattila, McCarthy, McCrohan, Mignatti, Mignatti, Miller, Mongiat, Montesano, Montesano, Morbidelli, Moscatelli, Nachman, Nguyen, Nico, Nicosia, Nurcombe, Ozaki, Padro, Parsons-Wingerter, Partridge, Passaniti, Pellegrini, Pendurthi, Peoples, Pepper, Pepper, Pepper, Perollet, Placanica, Polnaszek, Poole, Poon, Post, Presta, Presta, Presta, Presta, Presta, Presta, Pugh, Quarto, Rak, Reuss, Ria, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Rissanen, Rousseau, Ruegg, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Russo, Sahni, Sahni, Sahni, Sahni, Salgado, Salmivirta, Salustri, Schnaper, Schnaper, Seghezzi, Sellke, Senn, Sepp, Shaw, Sheibani, Shing, Shono, Shono, Simons, Simons, Singh, Souttou, Stokes, Syed, Tabata, Takahashi, Takei, Talarico, Tanghetti, Taraboletti, Taraboletti, Tassi, Taverna, Terranova, Tiefenbacher, Tille, Tobe, Tomanek, Ueno, Underwood, Unger, Vacca, Vlodavsky, Walford, Wang, Wang, Weidner, Weinstein, Wempe, Xu, Xue, Yamaguchi, Yamayoshi, Yoon, Zhang, Zhang, Zhao, Zhou, Zhou, Ziche, Ziche   +253 more
core   +1 more source

Vascular Endothelial Growth Factor [PDF]

Circulation Research, 2000
In this issue of Circulation Research , D’Arcangelo et al1 report highly interesting and unexpected results in that acidosis inhibits proliferation and migration of cultured endothelial cells, inhibits the formation of capillary tubes, but simultaneously increases expression of the endothelial growth factors vascular endothelial growth factor (VEGF ...
Matthias Clauss, Wolfgang Schaper
openaire   +1 more source

Arterial Blood Pressure Variability and Other Vascular Factors Contribution to the Cognitive Decline in Parkinson’s Disease

Molecules, 2021
Dementia is one of the most disabling non-motor symptoms in Parkinson’s disease (PD). Unlike in Alzheimer’s disease, the vascular pathology in PD is less documented.
Anna Pierzchlińska, Magdalena Kwaśniak-Butowska, Jarosław Sławek, Marek Droździk, Monika Białecka   +4 more
doaj   +1 more source

Age and diabetes related changes of the retinal capillaries: an ultrastructural and immunohistochemical study [PDF]

, 2015
Normal human aging and diabetes are associated with a gradual decrease of cerebral flow in the brain with changes in vascular architecture. Thickening of the capillary basement membrane and microvascular fibrosis are evident in the central nervous system
ARTICO, Marco, BATTAGLIONE, Ezio, BIANCHI, ENRICA, Feher, Janos, Kovacs, Illes, MAGLIULO, Giuseppe, Micera, Alessandra, ORLANDO, Maria Patrizia, PLATEROTI, Rocco, Ripandelli, Guido, TAURONE, SAMANTA   +10 more
core   +1 more source

Comparison of Continuous and Periodic Exercise on Serum Nitric Oxide Level and Vascular Endothelial Growth Factor in Old Rats [PDF]

Medical Laboratory Journal, 2023
Background and objectives: Considering the importance of aging and the associated physiological changes, as well as the effects of exercise on angiogenesis and cardiac index, this study aimed to compare continuous and periodic exercise in form of high ...
Abdolhamid Zokaei, Mehran Ghahramani, Golbano Bolouri, Mahdieh Nassiri Avanaki   +3 more
doaj  

Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]

, 2010
The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V., Jimenez, Sergio A., Piera-Velazquez, Sonsoles   +2 more
core   +2 more sources

The Lymphangiogenic Vascular Endothelial Growth Factors VEGF-C and -D Are Ligands for the Integrin α9β1*

Journal of Biological Chemistry, 2005
Mice homozygous for a null mutation of the integrin α9 subunit die 6–12 days after birth from bilateral chylothoraces suggesting an underlying defect in lymphatic development.
N. Vlahakis, B. Young, A. Atakilit, D. Sheppard   +3 more
semanticscholar   +1 more source

THE ROLE OF DYSLIPIDEMIA IN THE PROGRESSION OF DIABETIC RETINOPATHY

Медицинский совет, 2017
Angiogenesis factors, growth factors (vascular endothelial growth factor (VEGF), angiopoietin-2, insulin-like growth factor, etc.) and cytokines play the leading role in the production by endothelial cells of new retinal blood vessels, increased vascular
A. G. Kuzmin, S. A. Martynov, M. V. Shestakova   +2 more
doaj   +1 more source