Results 61 to 70 of about 3,154,071 (299)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Hand Biometric Recognition Based on Fused Hand Geometry and Vascular Patterns
Sensors, 2013 A hand biometric authentication method based on measurements of the user’s hand geometry and vascular pattern is proposed. To acquire the hand geometry, the thickness of the side view of the hand, the K-curvature with a hand-shaped chain code, the ...
Soowon Kim, GiTae Park
doaj +1 more source
PLoS ONE, 2020 BackgroundThe prognostic value of positive surgical margins after transoral laser microsurgery (TOLM) is still under debate. In case of positive superficial margins, some experts recommend a second-look surgery (SL) and some recommend wait and watch ...
Joanna Witkiewicz +4 more
doaj +1 more source
Role of Doppler Ultrasound in Differentiation between Benign and Malignant Lymph Nodes
SVU - International Journal of Medical Sciences, 2022 Background: A popular presenting symptom for a number of disorders is lymphadenopathy. Malignant and non-malignant lymphadenopathy differentiation has major clinical and therapeutic advantages.
Alaa Abdelhakim Taha Ahmed* +3 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
CADASIL: A monogenic condition causing stroke and subcortical vascular dementia [PDF]
, 2002 Mutations in Notch3 are the cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an inherited small vessel disease leading to subcortical strokes and vascular dementia. The phenotypic presentation
Dichgans, Martin
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Texas Pattern Jury Charges [PDF]
, 2011 Guide listing pattern jury charges to assist the bench and bar in preparing the court's charge for the jury in the state of Texas, including general instructions for the guilt/innocence and punishment stages of the trial, and instructions related to ...
State Bar of Texas. Committee on Pattern Jury Charges. +1 more
core
Brain Tumor Vascular Network Segmentation from Micro-Tomography [PDF]
, 2011 Micro-tomography produces high resolution images of bio- logical structures such as vascular networks. In this paper, we present a new approach for segmenting vascular network into pathological and normal regions from considering their micro-vessel 3D ...
Raphael Serduc +14 more
core +1 more source