Results 101 to 110 of about 258,579 (218)

Integrin α_v contributes to the regulation of vascular smooth muscle cell stiffness. [PDF]

Sci Rep
Bascetin R, Belozertseva E, Regnault V, Raoul A, Liu X, Tone CM, Karkhaneh-Yousefi AA, Louis H, Ramdane-Cherif Z, Lerognon C, Avril S, Lacy-Hulbert A, Henrion D, Lacaze E, Challande P, Li Z, Lacolley P.   +16 more
europepmc   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Vascular smooth muscle cell state trajectories mediate molecular mechanisms of coronary disease risk. [PDF]

Nat Commun
Li DY, Kundu S, Cheng P, Gu W, Worssam MD, Jackson WR, Zhao Q, Nguyen T, Yu AM, Monteiro JP, Caceres RD, Dale S, Palmisano BT, Weldy CS, Ramste M, Kundu R, Kundaje A, Wirka RC, Quertermous T.   +18 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Vascular smooth muscle cell metabolic reprogramming and phenotypic remodeling in atherosclerosis. [PDF]

Cell Death Discov
Fu Z, Yang S, Chang X, Liu P, Wang Y.
europepmc   +1 more source

A high‐fat diet with vitamin D and propylthiouracil produces a pro‐atherogenic phenotype in rats

Animal Models and Experimental Medicine, EarlyView.
Male Sprague–Dawley rats received a cholesterol‐rich high‐fat diet supplemented with vitamin D and propylthiouracil for 11 weeks. The model induced dyslipidemia (increased total cholesterol/low‐density lipoprotein, decreased triglycerides), inflammation (increased interleukin‐6 and serum amyloid A), hypercalcemia, and reduced circulating endothelial ...
Angélique Lewies, Vitaris Kodogo, Johannes Frederik Wentzel, Francis Edwin Smit   +3 more
wiley   +1 more source

The Metabolite Differences in Vascular Smooth Muscle Cells of Abdominal Aortic Aneurysm Revealed by Untargeted Metabolomics. [PDF]

Biomedicines
Yi Y, Hu K, Li Y, Li J, Deng H.
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Semaglutide reduces murine blood pressure through the vascular smooth muscle GLP-1 receptor. [PDF]

JCI Insight
Medak KD, Koehler JA, Baggio LL, Gonzalez-Rellan MJ, Wong CK, Cao X, Rao V, Kao S, Cui Y, Fu J, Liaw E, Kabir MG, Zhang J, Wei J, Drucker DJ.   +14 more
europepmc   +1 more source

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

Animal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang, Yan Zan, Tiantian Ma, Xiaoquan Huang, Junwei Li, Liangjun Xia, Yuping Sa, Youbing Xia   +7 more
wiley   +1 more source