Results 81 to 90 of about 2,150,532 (298)

Metal–Organic Framework‐Preserved Thermostable Microneedle Patch for Minimally Invasive Detection and Monitoring of Kidney Dysfunction

open access: yesAdvanced Materials, EarlyView.
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang   +10 more
wiley   +1 more source

The extracellular signal-regulated kinase (ERK) pathway: a potential therapeutic target in hypertension

open access: yesJournal of Experimental Pharmacology, 2012
Richard E RobertsSchool of Biomedical Sciences, University of Nottingham, Nottingham, United KingdomAbstract: Hypertension is a risk factor for myocardial infarction, stroke, renal failure, heart failure, and peripheral vascular disease.
Roberts RE
doaj  

Cell Autonomous and Non-cell Autonomous Regulation of SMC Progenitors in Pulmonary Hypertension

open access: yesCell Reports, 2018
Summary: Pulmonary hypertension is a devastating disease characterized by excessive vascular muscularization. We previously demonstrated primed platelet-derived growth factor receptor β+ (PDGFR-β+)/smooth muscle cell (SMC) marker+ progenitors at the ...
Abdul Q. Sheikh   +4 more
doaj   +1 more source

Expression of mRNA for phospholipase A(2), cyclooxygenases, and lipoxygenases in cultured human umbilical vascular endothelial and smooth muscle cells and in biopsies from umbilical arteries and veins [PDF]

open access: yes, 1998
Arachidonic acid (AA) is released by phospholipase A(2) (PLA(2)) and then converted into vasoactive and inflammatory eicosanoids by cyclooxygenases (COX) and lipoxygenases (LOX).
Söderkvist, Peter   +5 more
core   +1 more source

Deep‐Tissue Light Generation via Whispering Gallery Mode Lasing From a Commercial Nylon Fiber for Biomedical Applications

open access: yesAdvanced Materials Technologies, EarlyView.
A dyed nylon fiber is implemented inside the scattering phantom and skin tissue. The deep‐tissue light generation via whispering gallery mode lasing is demonstrated, achieving a depth of >50 times transport mean free path in scattering phantom and 3 mm beneath skin.
Dongqin Ni   +4 more
wiley   +1 more source

Cellular and molecular components of the atherosclerotic process: Primary colture and characterization of human vascular smooth muscle cells from carotid artery [PDF]

open access: yes, 2009
Introduction The last years were characterized by several studies proceeding to understand SMC heterogeneity. Animal models of rat or rabbit IT after endothelial lesion are presently the most studied models for atherosclerotic plaque formation and ...
Gagliano, Teresa
core  

Effects of 17β-oestradiol on rat detrusor smooth muscle contractility [PDF]

open access: yes, 2009
The aim of this study was to investigate the effect of 17β-oestradiol (E2) on detrusor smooth muscle contractility and its possible neuroprotective role against ischaemic-like condition, which could arise during overactive bladder disease.
Keith L. Brain   +19 more
core   +1 more source

A Constraint‐Based Analytical Framework for Design‐Space Analysis and Material Screening of Tubular Multilayer Dielectric Elastomer Pumps for Extracorporeal Circulatory Applications

open access: yesAdvanced Materials Technologies, EarlyView.
A constraint‐based analytical framework maps the coupled effects of material properties, structural parameters, and operating conditions in tubular dielectric elastomer pumps for extracorporeal circulatory applications. The approach defines performance boundaries through mechanical, electrical, and hydraulic constraints and identifies feasible design ...
Yan Zhang   +3 more
wiley   +1 more source

Increased neointimal thickening in dystrophin-deficient mdx mice.

open access: yesPLoS ONE, 2012
BackgroundThe dystrophin gene, which is mutated in Duchenne muscular dystrophy (DMD), encodes a large cytoskeletal protein present in muscle fibers. While dystrophin in skeletal muscle has been extensively studied, the function of dystrophin in vascular ...
Uwe Rauch   +5 more
doaj   +1 more source

Calcium Channels in Vascular Smooth Muscle [PDF]

open access: yes, 2017
Calcium (Ca2+) plays a central role in excitation, contraction, transcription, and proliferation of vascular smooth muscle cells (VSMs). Precise regulation of intracellular Ca2+ concentration ([Ca2+]i) is crucial for proper physiological VSM function.
D, Ghosh   +6 more
openaire   +2 more sources

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