Results 111 to 120 of about 769,970 (260)

Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells [PDF]

open access: yes, 2008
Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling.
Burnstock, G
core  

An essential requirement for β1 integrin in the assembly of extracellular matrix proteins within the vascular wall [PDF]

open access: yes, 2012
β1 integrin has been shown to contribute to vascular smooth muscle cell differentiation, adhesion and mechanosensation in vitro. Here we showed that deletion of β1 integrin at the onset of smooth muscle differentiation resulted in interrupted aortic arch,
Fassler, Reinhard   +6 more
core   +1 more source

A 3D-1D-0D Multiscale Model of the Neuro-Glial-Vascular Unit for Synaptic and Vascular Dynamics in the Dorsal Vagal Complex [PDF]

open access: yesarXiv
Cerebral blood flow regulation is critical for brain function, and its disruption is implicated in various neurological disorders. Many existing models do not fully capture the complex, multiscale interactions among neuronal activity, astrocytic signaling, and vascular dynamics--especially in key brainstem regions.
arxiv  

Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α.

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2014
RATIONALE Chronic hypoxia induces pulmonary vascular remodeling, pulmonary hypertension, and right ventricular hypertrophy. At present, little is known about mechanisms driving these responses.
M. Ball   +11 more
semanticscholar   +1 more source

Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins [PDF]

open access: yes, 2015
Vascular pathologies are associated with changes in the presence and expression of morphologically distinct vascular smooth muscle cells. In particular, in complex human vascular lesions and models of disease in pigs and rodents, an intimal smooth muscle
Arnold   +46 more
core   +2 more sources

Role of vascular smooth muscle cell in the inflammation of atherosclerosis

open access: yesBMB Reports, 2014
Atherosclerosis is a pathologic process occurring within the artery, in which many cell types, including T cell, macrophages, endothelial cells, and smooth muscle cells, interact, and cause chronic inflammation, in response to various inner- or outer ...
Soyeon Lim, Sungha Park
semanticscholar   +1 more source

Dipeptidyl peptidase-4 inhibitor gemigliptin protects against vascular calcification in an experimental chronic kidney disease and vascular smooth muscle cells.

open access: yesPLoS ONE, 2017
Although dipeptidyl peptidase-4 inhibitors, a class of antidiabetic drugs, have various pleiotropic effects, it remains undetermined whether gemigliptin has a beneficial effect on vascular calcification.
Soon-Youn Choi   +7 more
doaj   +1 more source

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