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Chemokine Receptors in Vascular Smooth Muscle

Microcirculation, 2003
ABSTRACTAtherosclerosis is considered to be an inflammatory disease. Chemokines are low‐molecular‐weight proteins that exert their effects, in part, through mediating leukocytic infiltration into the vessel wall. Recently, studies have determined that chemokines and their receptors are present, and function on other cellular components comprising the ...
Mark B. Taubman   +2 more
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Vascular Smooth Muscle

1996
Smooth Muscle Tissue. The visceral mesenchyma (splanchnopleura) is the principal source for smooth muscle tissue. It also forms the layer-shaped muscle and connective tissue strata of the vessel walls. The vascular system of the human embryo develops from blood islets in the middle of the third week, shortly before somite formation, when the embryo can
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Regulation of differentiation of vascular smooth muscle cells.

Physiological Reviews, 1995
The vascular smooth muscle cell (SMC) in mature animals is a highly specialized cell whose principal function is contraction. The fully differentiated or mature SMC proliferates at an extremely low rate and is a cell almost completely geared for ...
G. Owens
semanticscholar   +1 more source

Calcium Kinetics in Vascular Smooth Muscle

Chest, 1985
The accumulation, binding, and mobilization of Ca++ in vascular smooth muscle directly affects intracellular free Ca++ levels and contractility. Techniques have been developed to delineate Ca++ uptake and efflux parameters in isolated vessels. Similar Ca++-related components are present in different types of vessels, but their relative importance for ...
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Vascular smooth muscle and exercise

Sports Medicine, Training and Rehabilitation, 1998
Vascular smooth muscle is under the influence of local (metabolic, autoregulatory and endothelial), reflex (autonomic nervous system), and hormonal (norepinephrine, epinephrine, angioten‐sin, and vasopressin) regulatory mechanisms. These regulatory mechanisms interact during exercise in a coordinated manner to assure adequate tissue blood flow while ...
Stephen E. DiCarlo   +3 more
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Vascular smooth muscle and arterial calcification

Zeitschrift f�r Kardiologie, 2000
Smooth muscle cultures can calcify under certain circumstances. As a model system these cultures therefore provide information on why calcification occurs in atherosclerotic plaques. Whether all smooth muscle cells (under certain conditions), or only specific populations, can produce this mineralization has not been resolved.
Campbell, G. R., Campbell, J. H.
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Sarcoglycans in Vascular Smooth and Striated Muscle

Trends in Cardiovascular Medicine, 2003
Sarcoglycans are transmembrane proteins important in the maintenance of proper muscle function. Together, the sarcoglycans form a heteromeric complex that interacts with dystrophin, dystroglycan, and filamin C to form a mechanosignaling complex. Mutations in the genes encoding sarcoglycan can produce cardiomyopathy and muscular dystrophy.
Elizabeth M. McNally, Matthew T. Wheeler
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Ultrastructure of Vascular Smooth Muscle

2017
Vascular smooth muscle, which is located in the tunica media layer of the vascular wall, is the primary player to enable the blood vessel to constrict and dilate. This is fulfilled by the interaction of thin and thick filaments of the contractile apparatus. These filaments in the smooth muscle are organized differently from striated muscle, termed side
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Metabolism of Vascular Smooth Muscle

2017
Metabolism refers to chemical reactions that occur in living organisms necessary to maintain its structure and activities, to respond to environment changes, and to grow and reproduce. In this chapter we focus on the metabolism related to energy supply for the contractility of vascular smooth muscle (VSM), including the characteristics of energy ...
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Oxygen sensors in vascular smooth muscle

Journal of Applied Physiology, 1994
Inhibition or activation of cellular function due to acute decreases in PO2 can be considered in terms of two different processes: 1) a sensor that monitors PO2 decreases and 2) transduction systems directed from the O2 sensor to reactions that control cellular function.
W. S. Fillers   +3 more
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