Results 51 to 60 of about 769,970 (260)
Endothelial dysfunction is widely implicated in cardiovascular pathological changes and development of vascular disease. In view of the fact that the spontaneous endothelial cell (EC) regeneration is a slow and insufficient process, it is of great ...
X. Hong+6 more
semanticscholar +1 more source
Identification and Initial Functional Characterization of a Human Vascular Cell-Enriched Long Noncoding RNA [PDF]
OBJECTIVE: Long noncoding RNAs (lncRNAs) represent a rapidly growing class of RNA genes with functions related primarily to transcriptional and post-transcriptional control of gene expression. There is a paucity of information about lncRNA expression and
Bell, R. D.+10 more
core +1 more source
Camphorated p-chlorophenol-induced contractile dynamics in aortic rings of Wistar rats
Introduction: camphorated p-chlorophenol is a chlorophenolic derivative commonly used as an intra-oral medication in endodontics. Scientific reports on its effects in arterial vascular smooth muscle and local blood flow regulation are scarce. Objective:
Oscar Rodríguez-Reyes+4 more
doaj
Caveolin-3 promotes a vascular smooth muscle contractile phenotype
Epidemiological studies have demonstrated the importance of cardiovascular diseases in Western countries. Among the cell types associated with a dysfunctional vasculature, smooth muscle cells are believed to play an essential role in the development of ...
Jorge L. Gutierrez-Pajares+8 more
doaj +1 more source
RATIONALE Uncontrolled growth of abdominal aortic aneurysms (AAAs) is a life-threatening vascular disease without an effective pharmaceutical treatment. AAA incidence dramatically increases with advancing age in men.
Houzao Chen+15 more
semanticscholar +1 more source
Altered vascular smooth muscle function in the ApoE knockout mouse during the progression of atherosclerosis [PDF]
Objectives: Relaxation of vascular smooth muscle (VSM) requires re-uptake of cytosolic Ca2+ into the sarcoplasmic reticulum (SR) via the Sarco/Endoplasmic Reticulum Ca2+ ATPase (SERCA), or extrusion via the Plasma Membrane Ca2+ ATPase (PMCA) or sodium ...
Abhirami L.N. Raja+49 more
core +1 more source
Numerous studies have shown that the proliferation and apoptosis of vascular smooth muscle cells play a key role in restenosis. Artesunate is a triterpenoid with a peroxide structure and its antimalarial, antitumor, and antiangiogenetic activities can ...
Jingwen Zhang+7 more
doaj +1 more source
Measurements and System Identification for the Characterization of Smooth Muscle Cell Dynamics [PDF]
Biological tissue integrity is actively maintained by cells. It is essential to comprehend how cells accomplish this in order to stage tissue diseases. However, addressing the complexity of a cell's system of interrelated mechanisms poses a challenge.
arxiv +1 more source
Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells
Mural cells of the vessel wall, namely pericytes and vascular smooth muscle cells, are essential for vascular integrity. The developmental sources of these cells and molecular mechanisms controlling their progenitors in the heart are only partially ...
Qi Chen+9 more
semanticscholar +1 more source
Guidance Molecules in Vascular Smooth Muscle
Several highly conserved families of guidance molecules, including ephrins, Semaphorins, Netrins, and Slits, play conserved and distinct roles in tissue remodeling during tissue patterning and disease pathogenesis.
Alexandra Christine Finney+3 more
doaj +1 more source