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Vascular Smooth Muscle Remodeling in Conductive and Resistance Arteries in Hypertension.
Cardiovascular disease is a leading cause of death worldwide and accounts for >17.3 million deaths per year, with an estimated increase in incidence to 23.6 million by 2030. 1 Cardiovascular death represents 31% of all global deaths 2 -with stroke, heart
Isola A. M. Brown+8 more
semanticscholar +1 more source
Identification and Initial Functional Characterization of a Human Vascular Cell-Enriched Long Noncoding RNA [PDF]
OBJECTIVE: Long noncoding RNAs (lncRNAs) represent a rapidly growing class of RNA genes with functions related primarily to transcriptional and post-transcriptional control of gene expression. There is a paucity of information about lncRNA expression and
Bell, R. D.+10 more
core +1 more source
Endothelial–Vascular Smooth Muscle Cells Interactions in Atherosclerosis
Atherosclerosis is a chronic progressive inflammatory process that can eventually lead to cardiovascular disease (CVD). Despite available treatment, the prevalence of atherosclerotic CVD, which has become the leading cause of death worldwide, persists ...
Manna Li, M. Qian, Kathy Kyler, Jian Xu
semanticscholar +1 more source
MicroRNAs in pulmonary arterial remodeling [PDF]
Pulmonary arterial remodeling is a presently irreversible pathologic hallmark of pulmonary arterial hypertension (PAH). This complex disease involves pathogenic dysregulation of all cell types within the small pulmonary arteries contributing to vascular ...
A Courboulin+137 more
core +2 more sources
Role of endothelium in responses of vascular smooth muscle.
Robert F. Furchgott
openalex +2 more sources
Promoters to Study Vascular Smooth Muscle: Mistaken Identity?
Smooth muscle cells (SMCs) are a critical component of blood vessel walls that provide structural support, regulate vascular tone, and allow for vascular remodeling. These cells also exhibit a remarkable plasticity that contributes to vascular growth and
Raja Chakraborty+5 more
semanticscholar +1 more source
Maintenance of GLUT4 expression in smooth muscle prevents hypertension‐induced changes in vascular reactivity [PDF]
Previous studies have shown that expression of GLUT4 is decreased in arterial smooth muscle of hypertensive rats and mice and that total body overexpression of GLUT4 in mice prevents enhanced arterial reactivity in hypertension.
Atkins, Kevin B.+5 more
core +1 more source
Camphorated p-chlorophenol-induced contractile dynamics in aortic rings of Wistar rats
Introduction: camphorated p-chlorophenol is a chlorophenolic derivative commonly used as an intra-oral medication in endodontics. Scientific reports on its effects in arterial vascular smooth muscle and local blood flow regulation are scarce. Objective:
Oscar Rodríguez-Reyes+4 more
doaj
Caveolin-3 promotes a vascular smooth muscle contractile phenotype
Epidemiological studies have demonstrated the importance of cardiovascular diseases in Western countries. Among the cell types associated with a dysfunctional vasculature, smooth muscle cells are believed to play an essential role in the development of ...
Jorge L. Gutierrez-Pajares+8 more
doaj +1 more source
Endothelial dysfunction is widely implicated in cardiovascular pathological changes and development of vascular disease. In view of the fact that the spontaneous endothelial cell (EC) regeneration is a slow and insufficient process, it is of great ...
X. Hong+6 more
semanticscholar +1 more source