Vascular smooth muscle cell contractile function and mechanotransduction [PDF]
Vascular smooth muscle cells (VSMCs) are the predominant cell type in the arterial wall and normally adopt a quiescent, contractile phenotype to regulate vascular tone.
Ahmed, Sultan, Warren, Derek T.
core +1 more source
The Bone-Vascular Axis: A Key Player in Chronic Kidney Disease Associated Vascular Calcification
Background: The bone-vascular axis plays a key role in the pathogenesis of vascular calcification (VC) in patients with chronic kidney disease (CKD). Understanding and managing the role of the bone-vascular axis in CKD-mineral and bone disorder (CKD-MBD)
Yingjing Shen, Chen Yu
doaj +1 more source
Precise theranostic nanomedicines for inhibiting vulnerable atherosclerotic plaque progression through regulation of vascular smooth muscle cell phenotype switching [PDF]
Sai Ma +13 more
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Nitric oxide synthesis and biological functions of nitric oxide released from ruthenium compounds [PDF]
During three decades, an enormous number of studies have demonstrated the critical role of nitric oxide (NO) as a second messenger engaged in the activation of many systems including vascular smooth muscle relaxation.
ARAÚJO, A.V. +4 more
core +3 more sources
Circular RNA (circRNA) is a novel subgroup of noncoding RNA in the human transcriptome playing a vital role in the atherosclerosis of cerebrovascular disease.
Lei Yang +4 more
doaj +1 more source
Local regulation of the coronary circulation in health and disease: role of nitric oxide and endothelin [PDF]
Coronary artery disease is the leading cause of morbidity and mortality in western countries. Its pathogenesis is unknown, but involves enhanced vasoconstriction, increased interaction of platelets and monocytes with the vessel wall, as well as ...
Lüscher, T. F., Noll, G., Wenzel, R. R.
core
Yap1 Protein Regulates Vascular Smooth Muscle Cell Phenotypic Switch by Interaction with Myocardin [PDF]
Changqing Xie +5 more
openalex +1 more source
Survivin is a mechanosensitive cell cycle regulator in vascular smooth muscle cells [PDF]
John C. Biber +10 more
openalex +1 more source
Abstract To understand the function of arteries in the regulation of blood supply throughout the body it is essential to realize that the vessel wall is composed predominantly of smooth muscle cells (SMCs) with only one single layer of luminal endothelial cells.
Bochaton-Piallat, Marie-Luce +2 more
openaire +2 more sources
Although dipeptidyl peptidase-4 inhibitors, a class of antidiabetic drugs, have various pleiotropic effects, it remains undetermined whether gemigliptin has a beneficial effect on vascular calcification.
Soon-Youn Choi +7 more
doaj +1 more source

