Results 121 to 130 of about 385,157 (356)

Notch Signaling in Vascular Smooth Muscle Cells [PDF]

, 2017
The Notch signaling pathway is a highly conserved pathway involved in cell fate determination in embryonic development and also functions in the regulation of physiological processes in several systems. It plays an especially important role in vascular development and physiology by influencing angiogenesis, vessel patterning, arterial/venous ...
Jeremy T. Baeten, Brenda Lilly
openaire   +3 more sources

Design and use of an environmental control platform for studying vascular cell function in three-dimensional scaffolds [PDF]

, 2007
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.Includes bibliographical references (p. 33).Endothelial and smooth muscle cells are the core of the vascular system.
Jäätmaa, Iliana (Iliana Nicole Vera)
core  

Synthetic Bilirubin‐Based Nanomedicine Protects Against Renal Ischemia/Reperfusion Injury Through Antioxidant and Immune‐Modulating Activity

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
BX‐001N, a polyethylene glycol‐conjugated bilirubin 3α nanoparticle, is the first GMP‐grade, synthetic bilirubin‐based nanomedicine. It effectively attenuates acute renal injury, facilitates subacute renal recovery, and suppresses chronic fibrosis after renal ischemia/reperfusion injury via anti‐oxidant and immune‐modulating activity.
Ji‐Jing Yan, Hyunjin Kim, Bomin Kim, Honglin Piao, Joon Young Jang, Tae Kyeom Kang, Wook‐Bin Lee, Dohyeon Kim, Seunghyun Jo, Duckhyang Shin, Sharif MD Abuzar, Myung L. Kim, Jaeseok Yang, Sangyong Jon   +13 more
wiley   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Statins inhibited erythropoietin-induced proliferation of rat vascular smooth muscle cells [PDF]

, 2010
Erythropoietin (EPO) directly stimulates the proliferation of vascular smooth muscle cells, and this is believed to be one of the mechanisms of vascular access failure of hemodialysis patients. However, precise mechanisms of the EPO-induced proliferation
Fujimura Akio, Kaneda Tae, Tsuruoka Shuichi, 鶴岡 秀一   +3 more
core   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

Role of Ryanodine Type 2 Receptors in Elementary Ca2+ Signaling in Arteries and Vascular Adaptive Responses

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Hypertension is the major risk factor for cardiovascular disease, the most common cause of death worldwide. Resistance arteries are capable of adapting their diameter independently in response to pressure and flow‐associated shear stress ...
Mario Kaßmann, István András Szijártó, Concha F. García‐Prieto, Gang Fan, Johanna Schleifenbaum, Yoland‐Marie Anistan, Christoph Tabeling, Yu Shi, Ferdinand le Noble, Martin Witzenrath, Yu Huang, Lajos Markó, Mark T. Nelson, Maik Gollasch   +13 more
doaj   +1 more source

Binding of Extracellular Maspin to 1 Integrins Inhibits Vascular Smooth Muscle Cell Migration [PDF]

, 2009
Maspin is a serpin that has multiple effects on cell behavior, including inhibition of migration. How maspin mediates these diverse effects remains unclear, as it is devoid of protease inhibitory activity.
Akiyama, Al-Ayyoubi, Askari, Bailey, Bass, Bass, Bass, Becerra, Biliran, Blacque, Brown, Cella, Coe, Dollery, Filleur, Filleur, Galis, Gao, Humphries, Huntington, Häyry, Jiang, Khalkhali-Ellis, Laura Wagstaff, Law, Li, Li, Lorna Ravenhill, Luo, McGowen, Mould, Mould, Newby, Ngamkitidechakul, Odero-Marah, Owens, Pemberton, Pemberton, Rosemary Bass, Ross, Schreiner, Schwartz, Sechler, Seftor, Sheng, Sheng, Sheng, Shi, Shi, Smith, Stephens, Vincent Ellis, Yin, Zhang, Zou   +54 more
core   +2 more sources

Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins

Advanced Healthcare Materials, EarlyView.
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer, Amelia Hasenauer, Dominic Rütsche, Hao Liu, Jakub Janiak, Michael Nguyen, Karen L. Christman, Marcy Zenobi‐Wong, Parth Chansoria   +8 more
wiley   +1 more source

Guidance Molecules in Vascular Smooth Muscle

Frontiers in Physiology, 2018
Several highly conserved families of guidance molecules, including ephrins, Semaphorins, Netrins, and Slits, play conserved and distinct roles in tissue remodeling during tissue patterning and disease pathogenesis.
Alexandra Christine Finney, Anthony Wayne Orr, Anthony Wayne Orr, Anthony Wayne Orr   +3 more
doaj   +1 more source