Results 131 to 140 of about 385,157 (356)
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis +5 more
wiley +1 more source
Ion Channels and Their Regulation in Vascular Smooth Muscle [PDF]
, 2019 Vascular smooth muscle excitability is exquisitely regulated by different ion channels that control membrane potential (Em) and the magnitude of intracellular calcium inside the cell to induce muscle relaxation or contraction, which significantly ...
Le, Thanhmai +3 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Engineered 3D‐Cad/IL6‐MSC, developed through synergistic hE/N‐cad‐Fc and IL‐6 preconditioning, show remarkable therapeutic potential for systemic sclerosis. These engineered MSC aggregates reduce pathogenic inflammatory cell infiltration and restore immune balance among CD4+ T‐cell populations, offering a promising approach to optimize MSC based ...
Yue Zhang +11 more
wiley +1 more source
Linchuang shenzangbing zazhi, 2022 Vascular calcification （VC） is a major cause of cardiovascular mortality in patients with chronic kidney disease （CKD）. Current studies suggest that VC of CKD is not simply an ectopic deposition of calcium phosphate crystals in vascular wall.
Lu Yang-yang, Bai Ya-ling, Xu Jin-sheng
doaj
Stimulation of vascular smooth muscle cell prostacyclin and prostaglandin E2 synthesis by plasma high and low density lipoproteins. [PDF]
, 1984 Kenneth B. Pomerantz +3 more
openalex +1 more source
Smooth Muscle Progenitor Cells: Friend or Foe in Vascular Disease? [PDF]
The origin of vascular smooth muscle cells that accumulate in the neointima in vascular diseases such as transplant arteriosclerosis, atherosclerosis and restenosis remains subject to much debate.
de Kleijn, Dominique +4 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex +4 more
wiley +1 more source
Comparison of small proteoglycans from skin fibroblasts and vascular smooth-muscle cells [PDF]
, 1986 Uwe Rauch, Josef Glössl, Hans Kresse
openalex +1 more source
Vascular smooth muscle cell apoptosis in atherosclerosis [PDF]
International Journal of Experimental Pathology, 1999 Cell death has long been recognized within the vessel wall, in particular, in disease states such as atherosclerosis. The use of the term ‘necrotic core’ for the central lipid core of advanced lesions emphasizes this. Indeed there is obvious cell fragmentation and cell debris in areas of plaques, particularly the lipid core (Mitchinson et al.
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz +2 more
wiley +1 more source