Results 271 to 280 of about 236,813 (316)
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Leptin and Vascular Smooth Muscle Cells

Current Pharmaceutical Design, 2014
This review concerns the influence of leptin on vascular smooth muscle cells (VSMC). VSMC express different isoforms of the leptin receptor (Ob-R) able to activate a wide range of intracellular signalling pathways, mediating many relevant biological actions.
TROVATI, Mariella   +5 more
openaire   +3 more sources

Vascular smooth muscle cell in atherosclerosis

Acta Physiologica, 2015
AbstractVascular smooth muscle cells (VSMCs) exhibit phenotypic and functional plasticity in order to respond to vascular injury. In case of the vessel damage, VSMCs are able to switch from the quiescent ‘contractile’ phenotype to the ‘proinflammatory’ phenotype.
Chistiakov, Dimitry A.   +2 more
openaire   +3 more sources

Vascular Smooth Muscle Cells

2002
Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R.   +2 more
openaire   +1 more source

MicroRNA and Vascular Smooth Muscle Cells

2011
Vascular smooth muscle cells (VSMCs) exhibit extraordinary plasticity during postnatal development. Vascular injury initiates VSMC phenotypic switch from the contractile to proliferative phenotype, which plays a central role in vascular lesion formation and diverse vascular diseases.
Changqing, Xie   +2 more
openaire   +2 more sources

Human Vascular Smooth Muscle Cell Culture

2011
Human vascular smooth muscle cells (VSMCs) in culture are an important tool in understanding how VSMCs function and contribute to vessel wall contraction as well as disease. In this chapter, we describe methodologies that enable the investigator to culture large numbers of proliferative VSMCs.
Diane, Proudfoot, Catherine, Shanahan
openaire   +2 more sources

Carvedilol Inhibits Vascular Smooth Muscle Cell Proliferation

Journal of Cardiovascular Pharmacology, 1993
The antiproliferative properties of carvedilol, a newly developed multiple-action antihypertensive agent, were evaluated in early passage cultured rat aortic vascular smooth muscle cells. Carvedilol (10(-7)-10(-5) M) produced concentration-dependent decreases in basal and endothelin-1-stimulated mitogenesis of rat aortic vascular smooth muscle cells ...
C P, Sung, A J, Arleth, E H, Ohlstein
openaire   +2 more sources

Lysolecithin actions on vascular smooth muscle cells

Biochemical and Biophysical Research Communications, 1992
Oxidation of low density lipoprotein increases its atherogenic potential. During oxidation there is an extensive conversion of lecithin to lysolecithin. In rat aortic smooth muscle cells, 2-25 micrograms/ml lysolecithin elevated cytosolic calcium concentration up to 560%.
R, Locher   +4 more
openaire   +2 more sources

Sodium Cotransport in Vascular Smooth Muscle Cells

Journal of Vascular Research, 1991
Vascular smooth muscle cells possess a number of Na cotransport systems. Three of these cotransport systems, Na/Ca exchange, Na/H exchange and Na-K-Cl cotransport, have been the subject of an increasing number of investigations to determine the respective roles of these transporters in vascular smooth muscle cell function.
M E, O'Donnell, N E, Owen
openaire   +2 more sources

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