Results 271 to 280 of about 236,813 (316)
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Leptin and Vascular Smooth Muscle Cells
Current Pharmaceutical Design, 2014This review concerns the influence of leptin on vascular smooth muscle cells (VSMC). VSMC express different isoforms of the leptin receptor (Ob-R) able to activate a wide range of intracellular signalling pathways, mediating many relevant biological actions.
TROVATI, Mariella +5 more
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Vascular smooth muscle cell in atherosclerosis
Acta Physiologica, 2015AbstractVascular smooth muscle cells (VSMCs) exhibit phenotypic and functional plasticity in order to respond to vascular injury. In case of the vessel damage, VSMCs are able to switch from the quiescent ‘contractile’ phenotype to the ‘proinflammatory’ phenotype.
Chistiakov, Dimitry A. +2 more
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2002
Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R. +2 more
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Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R. +2 more
openaire +1 more source
MicroRNA and Vascular Smooth Muscle Cells
2011Vascular smooth muscle cells (VSMCs) exhibit extraordinary plasticity during postnatal development. Vascular injury initiates VSMC phenotypic switch from the contractile to proliferative phenotype, which plays a central role in vascular lesion formation and diverse vascular diseases.
Changqing, Xie +2 more
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Human Vascular Smooth Muscle Cell Culture
2011Human vascular smooth muscle cells (VSMCs) in culture are an important tool in understanding how VSMCs function and contribute to vessel wall contraction as well as disease. In this chapter, we describe methodologies that enable the investigator to culture large numbers of proliferative VSMCs.
Diane, Proudfoot, Catherine, Shanahan
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Carvedilol Inhibits Vascular Smooth Muscle Cell Proliferation
Journal of Cardiovascular Pharmacology, 1993The antiproliferative properties of carvedilol, a newly developed multiple-action antihypertensive agent, were evaluated in early passage cultured rat aortic vascular smooth muscle cells. Carvedilol (10(-7)-10(-5) M) produced concentration-dependent decreases in basal and endothelin-1-stimulated mitogenesis of rat aortic vascular smooth muscle cells ...
C P, Sung, A J, Arleth, E H, Ohlstein
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Lysolecithin actions on vascular smooth muscle cells
Biochemical and Biophysical Research Communications, 1992Oxidation of low density lipoprotein increases its atherogenic potential. During oxidation there is an extensive conversion of lecithin to lysolecithin. In rat aortic smooth muscle cells, 2-25 micrograms/ml lysolecithin elevated cytosolic calcium concentration up to 560%.
R, Locher +4 more
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Sodium Cotransport in Vascular Smooth Muscle Cells
Journal of Vascular Research, 1991Vascular smooth muscle cells possess a number of Na cotransport systems. Three of these cotransport systems, Na/Ca exchange, Na/H exchange and Na-K-Cl cotransport, have been the subject of an increasing number of investigations to determine the respective roles of these transporters in vascular smooth muscle cell function.
M E, O'Donnell, N E, Owen
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