Results 81 to 90 of about 396,621 (256)

Perivascular adipose tissue inflammation in vascular disease [PDF]

open access: yes, 2017
Perivascular adipose tissue (PVAT) plays a critical role in the pathogenesis of cardiovascular disease. In vascular pathologies, perivascular adipose tissue increases in volume and becomes dysfunctional, with altered cellular composition and molecular ...
Guzik, Tomasz J., Nosalski, Ryszard
core   +1 more source

The T2238C human atrial natriuretic peptide molecular variant and the risk of cardiovascular diseases [PDF]

open access: yes, 2018
Atrial natriuretic peptide (ANP) is a cardiac hormone which plays important functions to maintain cardio-renal homeostasis. The peptide structure is highly conserved among species. However, a few gene variants are known to fall within the human ANP gene.
Bianchi, Franca   +5 more
core   +5 more sources

How vascular smooth muscle cell phenotype switching contributes to vascular disease

open access: yesCell Communication and Signaling, 2022
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier experiments have found that VSMCs possess high plasticity. Vascular injury stimulates VSMCs to switch into a dedifferentiated type, also known as synthetic VSMCs, with a ...
Genmao Cao   +5 more
doaj   +1 more source

Notch and Vascular Smooth Muscle Cell Phenotype [PDF]

open access: yesCirculation Research, 2008
The Notch signaling pathway is critical for cell fate determination during embryonic development, including many aspects of vascular development. An emerging paradigm suggests that the Notch gene regulatory network is often recapitulated in the context of phenotypic modulation of vascular smooth muscle cells (VSMC), vascular remodeling, and repair in ...
David A. Morrow   +8 more
openaire   +3 more sources

Endothelial and smooth muscle cell interactions with a PCL-PU composite vascular scaffold with potential for bioactive release [PDF]

open access: yes, 2006
Paper discussing endothelial and smooth muscle cell interactions with a PCL-PU composite vascular scaffold with potential for bioactive ...
Black, Richard   +2 more
core  

Endothelial dysfunction and vascular disease [PDF]

open access: yes, 2009
The endothelium can evoke relaxations (dilatations) of the underlying vascular smooth muscle, by releasing vasodilator substances. The best characterized endothelium-derived relaxing factor (EDRF) is nitric oxide (NO).
Abeywardena   +460 more
core   +1 more source

Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFß receptor phosphorylation [PDF]

open access: yes, 2012
The signaling pathways that regulate the synthesis and structure of proteoglycans secreted by vascular smooth muscle cells are potential therapeutic targets for preventing lipid deposition in the early stage of atherosclerosis.
Ballinger, M   +9 more
core  

Differing calcification processes in cultured vascular smooth muscle cells and osteoblasts [PDF]

open access: yes, 2019
© 2019 Published by Elsevier Inc.Arterial medial calcification (AMC) is the deposition of calcium phosphate mineral, often as hydroxyapatite, inthe medial layer of the arteries.
Arnett, Timothy R   +6 more
core   +5 more sources

Angiotensin II-mediated vascular smooth muscle cell growth signaling

open access: yesBrazilian Journal of Medical and Biological Research, 2000
The mechanism by which Ang II stimulates the growth of vascular smooth muscle cells was investigated by measuring the phosphorylation of mitogen-activated protein kinases ERK 1 and ERK 2.
T. Inagami, S. Eguchi
doaj   +1 more source

Extreme Diversity of the Human Vascular Mesenchymal Cell Landscape

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Human mesenchymal cells are culprit factors in vascular (patho)physiology and are hallmarked by phenotypic and functional heterogeneity.
Laura E. Bruijn   +4 more
doaj   +1 more source

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