Results 81 to 90 of about 242,639 (216)
RhoA activation by hypoxia in pulmonary arterial smooth muscle cells is age and site specific
Hypoxia induces vasoconstriction of pulmonary arteries through contraction of smooth muscle cells (SMCs). The GTPase RhoA regulates smooth muscle contractility and actin cytoskeletal remodeling through the Rho-associated kinase ( ROCK).
Bailly, K +6 more
core +1 more source
Fibrinogen is chemotactic for vascular smooth muscle cells
We studied the effect of fibrinogen on the migration of bovine aortic smooth muscle cells in culture, using a Neuro Probe 48‐well micro chemotaxis chamber. Fibrinogen stimulated the migration of the cells dose‐dependently at concentrations from 30 to 1OOO μg/ml.
Naito, Michitaka +5 more
openaire +2 more sources
Study of calcium sparks in skeletal and smooth muscle cells in normal and pathological conditions [PDF]
mTOR signaling influence a wide range of cellular process including protein synthesis (Iadevaia et al., 2012; Ma and Blenis, 2009; Thoreen et al., 2012), lipids synthesis (Lamming and Sabatini, 2013), transcription (Dibble and Manning, 2013; Vazquez ...
López, Rubén
core +1 more source
Vascular smooth muscle cell apoptosis in atherosclerosis [PDF]
Cell death has long been recognized within the vessel wall, in particular, in disease states such as atherosclerosis. The use of the term ‘necrotic core’ for the central lipid core of advanced lesions emphasizes this. Indeed there is obvious cell fragmentation and cell debris in areas of plaques, particularly the lipid core (Mitchinson et al.
openaire +2 more sources
Protein changes associated with embryonic stem cell differentiation to vascular smooth muscle cells
PhDEmbryonic stem (ES) cells can differentiate into many different cell lines, including vascular smooth muscle cells (SMCs). The aim of this project is to characterize protein changes during this differentiation process.
Yin, Xiaoke
core
MODULATION OF CALCIUM CHANNELS IN ARTERIAL SMOOTH-MUSCLE CELLS BY DIHYDROPYRIDINE ENANTIOMERS [PDF]
The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear ...
S Hering +7 more
core +1 more source
Angiotensin II-mediated vascular smooth muscle cell growth signaling
The mechanism by which Ang II stimulates the growth of vascular smooth muscle cells was investigated by measuring the phosphorylation of mitogen-activated protein kinases ERK 1 and ERK 2.
T. Inagami, S. Eguchi
doaj +1 more source
Notch Signaling in Vascular Smooth Muscle Cells [PDF]
The Notch signaling pathway is a highly conserved pathway involved in cell fate determination in embryonic development and also functions in the regulation of physiological processes in several systems. It plays an especially important role in vascular development and physiology by influencing angiogenesis, vessel patterning, arterial/venous ...
J T, Baeten, B, Lilly
openaire +2 more sources
cGMP Signaling and Vascular Smooth Muscle Cell Plasticity
Cyclic GMP regulates multiple cell types and functions of the cardiovascular system. This review summarizes the effects of cGMP on the growth and survival of vascular smooth muscle cells (VSMCs), which display remarkable phenotypic plasticity during the ...
Moritz Lehners +3 more
doaj +1 more source
In this study, we compared the potencies of diosgenin, a plant-derived sapogenin structurally similar to estrogen and progesterone, on vascular smooth muscle functions ranging from contraction and migration to apoptosis.
Cornelis van Breemen +17 more
core +1 more source

