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OGT-mediated O-GlcNAcylation of MAGI1 exacerbates high glucose-triggered inflammation and dedifferentiation of vascular smooth muscle cells by activating the PI3K/AKT pathway. [PDF]
Wen L, Dai R, Yu S, Yu H.
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ALOX5 regulates vascular smooth muscle cells pyroptosis to affect abdominal aortic aneurysm formation. [PDF]
Wang L, Wang B.
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Leptin and Vascular Smooth Muscle Cells
Current Pharmaceutical Design, 2014This review concerns the influence of leptin on vascular smooth muscle cells (VSMC). VSMC express different isoforms of the leptin receptor (Ob-R) able to activate a wide range of intracellular signalling pathways, mediating many relevant biological actions.
TROVATI, Mariella +5 more
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Vascular smooth muscle cell in atherosclerosis
Acta Physiologica, 2015AbstractVascular smooth muscle cells (VSMCs) exhibit phenotypic and functional plasticity in order to respond to vascular injury. In case of the vessel damage, VSMCs are able to switch from the quiescent ‘contractile’ phenotype to the ‘proinflammatory’ phenotype.
Chistiakov, Dimitry A. +2 more
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2002
Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R. +2 more
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Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R. +2 more
openaire +1 more source
MicroRNA and Vascular Smooth Muscle Cells
2011Vascular smooth muscle cells (VSMCs) exhibit extraordinary plasticity during postnatal development. Vascular injury initiates VSMC phenotypic switch from the contractile to proliferative phenotype, which plays a central role in vascular lesion formation and diverse vascular diseases.
Changqing, Xie +2 more
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Human Vascular Smooth Muscle Cell Culture
2011Human vascular smooth muscle cells (VSMCs) in culture are an important tool in understanding how VSMCs function and contribute to vessel wall contraction as well as disease. In this chapter, we describe methodologies that enable the investigator to culture large numbers of proliferative VSMCs.
Diane, Proudfoot, Catherine, Shanahan
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Carvedilol Inhibits Vascular Smooth Muscle Cell Proliferation
Journal of Cardiovascular Pharmacology, 1993The antiproliferative properties of carvedilol, a newly developed multiple-action antihypertensive agent, were evaluated in early passage cultured rat aortic vascular smooth muscle cells. Carvedilol (10(-7)-10(-5) M) produced concentration-dependent decreases in basal and endothelin-1-stimulated mitogenesis of rat aortic vascular smooth muscle cells ...
C P, Sung, A J, Arleth, E H, Ohlstein
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