Results 231 to 240 of about 236,796 (264)

Vascular smooth muscle cells

2017
Abstract To understand the function of arteries in the regulation of blood supply throughout the body it is essential to realize that the vessel wall is composed predominantly of smooth muscle cells (SMCs) with only one single layer of luminal endothelial cells.
Piallat, Marie-Luce, de Vries, Carlie JM, van Eys, Guillaume J   +2 more
openaire   +2 more sources

Vascular Smooth Muscle Cells

2002
Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R., Efendy, J., Campbell, J. H.   +2 more
openaire   +2 more sources

Endothelin degradation by vascular smooth muscle cells

Regulatory Peptides, 1996
The mechanism(s) of degradation of the potent vasoconstrictor endothelin-1 (ET-1) by rat vascular smooth muscle A-10 cells, which possess the ETA receptor subtype, was investigated by incubating [125I]ET-1 (0.1 nM) with cells for 0-4 h at 37 degrees C in the presence and absence of lysosomal enzyme inhibitors, NH4Cl and chloroquine, and a neutral ...
H, Bermek, K C, Peng, K, Angelova, A, Ergul, D, Puett   +4 more
openaire   +2 more sources

Sodium Cotransport in Vascular Smooth Muscle Cells

Blood Vessels, 2008
Vascular smooth muscle cells possess a number of Na cotransport systems. Three of these cotransport systems, Na/Ca exchange, Na/H exchange and Na-K-Cl cotransport, have been the subject of an increasing number of investigations to determine the respective roles of these transporters in vascular smooth muscle cell function.
M E, O'Donnell, N E, Owen
openaire   +2 more sources

Pathophysiological Role of the Vascular Smooth Muscle Cell

Journal of Cardiovascular Pharmacology, 1990
The vascular smooth muscle cell of the arterial media plays a predominant role in functional and structural alterations of the arterial wall in pathophysiological processes such as arterial hypertension, atheroma, or normal aging. The observed alterations are related to the three activities of the vascular smooth muscle cell, namely contractility ...
J B, Michel, N, De Roux, D, Plissonnier, S, Anidjar, J L, Salzmann, B, Levy   +5 more
openaire   +2 more sources

Apoptosis of vascular smooth muscle cells in atherosclerosis

Atherosclerosis, 1998
Apoptosis (programmed cell death) of vascular smooth muscle cells and macrophages has recently been demonstrated in the following: (a) human atherosclerotic plaques; (b) physiological remodelling of the vessel; and (c) a variety of disease states. Apoptosis is a highly regulated mechanism of death, controlled by the interactions between the following: (
M R, Bennett, J J, Boyle
openaire   +2 more sources

Smooth Muscle Progenitor Cells in Vascular Disease

Trends in Cardiovascular Medicine, 2004
Vascular smooth muscle cells have long been described as phenotypically diverse, with some populations possessing the potential for monoclonal expansion within the adult vessel wall. Recent experimental and human data suggest a potential role in atherosclerotic plaque, transplant arteriopathy, and angiogenesis biology for putative smooth muscle ...
Chunsheng, Liu, Karl A, Nath, Zvonimir S, Katusic, Noel M, Caplice   +3 more
openaire   +2 more sources

Thrombin and Proliferation of Vascular Smooth Muscle Cells

Circulation Research, 1995
Thrombin is a well-established promoter of vascular SMC proliferation in vitro. A similar role has been suggested but not yet proven in vivo. The effect is mediated via selective receptors expressed on vascular SMCs in vitro. Activation of the thrombin receptor leads to a number of intracellular signaling events as well as to stimulation of endogenous ...
openaire   +2 more sources

Phenotypic Switching of Vascular Smooth Muscle Cells in Atherosclerosis

Journal of the American Heart Association, 2023
Shu Ye, David Graham Mcvey, Xiaoxin Huang   +2 more
exaly  

Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells

Circulation Research, 2021
Mengcheng Shen, Michael Fischbein, Wu Jc   +2 more
exaly