Results 221 to 230 of about 6,256,490 (293)

Targeting modulated vascular smooth muscle cells in atherosclerosis via FAP-directed immunotherapy. [PDF]

Science
Amrute JM, Jung IH, Yamawaki T, Lin WL, Bredemeyer A, Diekmann J, Hayat S, Zhang X, Wakefield DL, Luo X, Maryam S, Heo GS, Yang S, Lee CJM, Wang C, Chou C, Kuppe C, Cook KD, Kovacs A, Chintalgattu V, Pruitt D, Barreda J, Stitziel NO, Cheng P, Liu Y, Kramann R, Kreisel D, Foo RS, Rulifson IC, Martin S, Grunert D, Thomas M, Cui J, Quertermous T, Bengel FM, Jackson S, Li CM, Ason B, Lavine KJ.   +38 more
europepmc   +1 more source

Baseline podocyte‐associated state and persistent cell–matrix transcriptional programs are associated with BALB/c substrain differences in adriamycin nephropathy

Animal Models and Experimental Medicine, EarlyView.
Two closely related BALB/c substrains exhibit different early responses to adriamycin (ADR)‐induced nephropathy. BALB/cByJcl mice showed lower baseline WT1‐positive nuclei counts and NPHS1 immunoreactivity than BALB/cAJcl mice, together with extracellular matrix and integrin programs that were enriched at baseline and persisted at Day 5.
Ryuya Nakagawa, Masaki Watanabe, Koyuki Kawamoto, Momoka Hiratsuka, Takeru Sasaki, Nobuya Sasaki   +5 more
wiley   +1 more source

Beyond Simple Mimicry: Next‐Generation Geometric Architectures and Future Paradigms in Small‐Molecule and Macrocyclic Peptidomimetics

Angewandte Chemie, EarlyView.
Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee, Sumin Son, Jeong Yeon Yoo, Ji Hyae Lee, Meehyun Chun, Seung Bum Park   +5 more
wiley   +2 more sources

Dopamine D1-like and Angiotensin II Type 1 Receptors Counter-Regulate Autophagy and Cell Proliferation in Rat Embryonic Thoracic Vascular Smooth Muscle Cells. [PDF]

Int J Mol Sci
Lee H, Lu A, Qaddumi WN, Amatya B, Polzin J, Verma M, Cadme RC, Felder RA, Armando I, Kopp JB, Jose PA.   +10 more
europepmc   +1 more source

Scaffold‐Free Living Cellular Structure With Omnidirectional Architectures

Advanced NanoBiomed Research, EarlyView.
Hydrogel lumen confinement enables the direct formation of mechanically stable, scaffold‐free cellular filaments under entirely aqueous, phototoxicity‐free conditions. These processable living building blocks support omnidirectional assembly into complex three‐dimensional architectures, providing a simple and versatile platform for scaffold‐free ...
Jing Ma, Shanshan Zhang, Xiaokang Deng, Cheng Qi, Haifeng Dong, Zhou Liu, Si Meng, Tiantian Kong   +7 more
wiley   +1 more source

ChemR23 prevents phenotypic switching of vascular smooth muscle cells into macrophage-like foam cells in atherosclerosis. [PDF]

Cardiovasc Res
Evans BR, Schulz J, Triantafyllidou V, Yerly A, Thakur M, Angliker N, Siegrist M, Jansen Y, Yan Y, Maas SL, Gold C, Farina FM, Bayer B, Bartelt A, Weber C, Wettich J, Maegdefessel L, Sachs N, Schindewolf M, Kotelis D, Noels H, Santovito D, van der Vorst EPC, Döring Y.   +23 more
europepmc   +1 more source

Silk Fibroin for Cardiovascular Medical Devices: Review of Material Properties, Applications, and Clinical Potential

Advanced NanoBiomed Research, EarlyView.
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab, Matt Govendir, Kristina Andelovic, Zachary Och, Fatemeh Karimi, Munira Xaymardan, Tomasz Jungst, Jelena Rnjak‐Kovacina, Nona Farbehi   +8 more
wiley   +1 more source

CNN3 promotes vascular smooth muscle cells proliferation and migration to deteriorate atherosclerosis by β-catenin signaling pathway. [PDF]

Atheroscler Plus
Zhang RY, Wu CM, Chen JJ, Li LX, Pang SY.   +4 more
europepmc   +1 more source

Correction: TSPO ligands prevent the proliferation of vascular smooth muscle cells and attenuate neointima formation through AMPK activation. [PDF]

Acta Pharmacol Sin
Wu LP, Gong ZF, Wang H, Zhou ZS, Zhang MM, Liu C, Ren HM, Yang J, Han Y, Zeng CY.   +9 more
europepmc   +1 more source

Preventive and inhibitory effects of <i>Salacia</i> on sustained contraction of vascular smooth muscle cells and characterization of the active compounds. [PDF]

Biochem Biophys Rep
Kajiya K, Inokuchi H, Sakakibara Y, Takamatsu H, Yamanouchi H.   +4 more
europepmc   +1 more source