Results 301 to 310 of about 428,994 (362)

A Subset of Pro‐inflammatory CXCL10+ LILRB2+ Macrophages Derives From Recipient Monocytes and Drives Renal Allograft Rejection

open access: yesAdvanced Science, EarlyView.
This study uncovers a recipient‐derived monocyte‐to‐macrophage trajectory that drives inflammation during kidney transplant rejection. Using over 150 000 single‐cell profiles and more than 850 biopsies, the authors identify CXCL10+ macrophages as key predictors of graft loss.
Alexis Varin   +16 more
wiley   +1 more source

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

open access: yesAdvanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su   +18 more
wiley   +1 more source

Contact Force Estimation of Continuum Robots without Embedded Sensors: A Review

open access: yesAdvanced Intelligent Systems, EarlyView.
This review surveys methods for estimating contact forces in continuum robots without embedded sensors. It explains why contact force matters, classifies force patterns, and groups existing methods into three approaches based on actuation, deformation, and environment information.
An Hu, Yu Sun
wiley   +1 more source

Elevated Dickkopf 3 Promotes Abdominal Aortic Aneurysm Formation via Modulated Phenotype Switch of Vascular Smooth Muscle Cells. [PDF]

open access: yesResearch (Wash D C)
Cao X   +15 more
europepmc   +1 more source

Bio‐to‐Robot Transfer of Fish Sensorimotor Dynamics via Interpretable Model

open access: yesAdvanced Intelligent Systems, EarlyView.
This study demonstrates how a biologically interpretable model trained on real‐fish muscle activity can accurately predict the motion of a robotic fish. By linking real‐fish sensorimotor dynamics with robotic fish, the work offers a transparent, data‐efficient framework for transferring biological intelligence to bioinspired robotic systems.
Waqar Hussain Afridi   +6 more
wiley   +1 more source

SREBP1 deficiency aggravates vascular calcification via iASPP-triggered ferroptosis of vascular smooth muscle cells. [PDF]

open access: yesCardiovasc Diabetol
Wu Y   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy