Results 41 to 50 of about 7,952,783 (243)

A Surgical Perspective on Targeted Therapy of Hepatocellular Carcinoma. [PDF]

open access: yes, 2015
Hepatocellular carcinoma (HCC), the second leading cause of cancer deaths worldwide, is difficult to treat and highly lethal. Since HCC is predominantly diagnosed in patients with cirrhosis, treatment planning must consider both the severity of liver ...
Busuttil, Ronald W   +2 more
core   +2 more sources

Vascular targeting agents

open access: yesInternational Journal of Radiation Oncology*Biology*Physics, 2002
International Journal of Radiation Oncology, Biology, Physics 54 (2002) 1472-1472.
Department of Radiation Oncology, University of Florida Shands Cancer Center, Gainesville, FLUSA ( host institution )   +1 more
openaire   +2 more sources

Targeting Vascular Calcification in Chronic Kidney Disease

open access: yesJACC: Basic to Translational Science, 2020
Central ...
A. Nelson   +5 more
semanticscholar   +1 more source

In Vivo Fluorescence Imaging of E-Selectin: Quantitative Detection of Endothelial Activation in Arthritis [PDF]

open access: yes, 2010
Rheumatoid arthritis (RA) is a chronic progressive systemic inflammatory disease, characterized by synovial inflammation and localized destruction of cartilage and bone.
Gompels, Luke, Gompels, Luke
core   +1 more source

Recent advances of nanotechnology-based tumor vessel-targeting strategies

open access: yesJournal of Nanobiotechnology, 2021
Tumor vessels can provide oxygen and nutrition for solid tumor tissue, create abnormal tumor microenvironment (TME), and play a vital role in the development, immune escape, metastasis and drug resistance of tumor.
Dongjie Zhu   +8 more
doaj   +1 more source

Awake chronic mouse model of targeted pial vessel occlusion via photothrombosis [PDF]

open access: yes, 2020
Animal models of stroke are used extensively to study the mechanisms involved in the acute and chronic phases of recovery following stroke. A translatable animal model that closely mimics the mechanisms of a human stroke is essential in understanding ...
Boas, David A.   +9 more
core   +1 more source

Rat Tumor Response to the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid as Measured by Dynamic Contrast-Enhanced Magnetic Resonance Imaging, Plasma 5-Hydroxyindoleacetic Acid Levels, and Tumor Necrosis

open access: yesNeoplasia: An International Journal for Oncology Research, 2006
The dose-dependent effects of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) on rat GH3 prolactinomas were investigated in vivo. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) was used to assess tumor blood flow/permeability pretreatment ...
Lesley D. McPhail   +6 more
doaj   +1 more source

Targeted treatment of vascular anomalies

open access: yesInternational Journal of Women's Dermatology, 2021
Vascular anomalies comprise an array of congenital developmental disorders that can lead to significant disfigurement and physiologic disarray. The vast multitude of clinical phenotypes has inherently led to misdiagnosis and patients and families enduring long diagnostic odysseys of medical care.
Ashley T. Ng   +2 more
openaire   +3 more sources

The Vascular-Ablative Agent VEGF121/rGel Inhibits Pulmonary Metastases of MDA-MB-231 Breast Tumors

open access: yesNeoplasia: An International Journal for Oncology Research, 2005
VEGF121/rGel, a fusion protein composed of the growth factor VEGF121 and the recombinant toxin gelonin (rGel), targets the tumor neovasculature and exerts impressive cytotoxic effects by inhibiting protein synthesis.
Sophia Ran   +4 more
doaj   +1 more source

The Microtubule-Targeting Agent Pretubulysin Impairs the Inflammatory Response in Endothelial Cells by a JNK-Dependent Deregulation of the Histone Acetyltransferase Brd4

open access: yesCells, 2023
The anti-inflammatory effects of depolymerizing microtubule-targeting agents on leukocytes are known for a long time, but the potential involvement of the vascular endothelium and the underlying mechanistic basis is still largely unclear.
Tobias F. Primke   +10 more
doaj   +1 more source

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