Results 101 to 110 of about 560,736 (342)
Osteogenic preconditioning in perfusion bioreactors improves vascularization and bone formation by human bone marrow aspirates. [PDF]
, 2020 Cell-derived extracellular matrix (ECM) provides a niche to promote osteogenic differentiation, cell adhesion, survival, and trophic factor secretion.
Genetos, DC +6 more
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cells, 2019 : Engineering of functional tissue, by combining either autologous or allogeneic cells with biomaterials, holds promise for the treatment of various diseases and injuries. Prevascularization of the engineered tissue was shown to enhance and improve graft
Luba Perry +3 more
doaj +1 more source
Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model : experimental study [PDF]
, 2019 Objective: Full-thickness cutaneous wounds treated with split-thickness skin grafts often result in unaesthetic and hypertrophic scars. Dermal substitutes are currently used together with skin grafts in a single treatment to reconstruct the dermal layer ...
Amos +37 more
core +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Características histológicas del útero de Sympterygia acuta (Garman, 1877) y Sympterygia bonapartii (Müller & Henle, 1841) (Chondrichthyes; Rajidae) [PDF]
, 2013 Los condrictios constituyen un clado sumamente conservado y vulnerable a la explotación, que ha cobrado una importancia creciente en los últimos años. Sin embargo, existe poca información sobre los aspectos morfológicos relacionados con la reproducción ...
Díaz Andrade, María Constanza +2 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo
Frontiers in Bioengineering and Biotechnology, 2019 The use of biomaterials and signaling molecules to induce bone formation is a promising approach in the field of bone tissue engineering. Follistatin (FST) is a glycoprotein able to bind irreversibly to activin A, a protein that has been reported to ...
Shorouk Fahmy-Garcia +14 more
doaj +1 more source
Risk stratification of neck lesions detected sonographically during the follow-up of differentiated thyroid cancer [PDF]
, 2016 Context: The European Thyroid Association (ETA) has classified post-treatment cervical ultrasound findings in thyroid cancer patients based on their association with disease persistence/recurrence.
BIFFONI, Marco +12 more
core +1 more source