Results 101 to 110 of about 33,455 (307)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Push-Dose Adrenaline versus Ephedrine for the Management of Intraoperative Hypotension: A Retrospective Observational Study

Bali Journal of Anesthesiology
Background: Intraoperative hypotension (IOH) is common during anesthesia and is associated with adverse postoperative outcomes. Ephedrine is widely used to treat acute IOH, while push-dose adrenaline has emerged as a potential alternative, offering rapid
Muhamad Rafiqi Hehsan, Chia Ying Chew, Kamaruddin Ibrahim, Mohammad Haizar Khan Haidar Khan   +3 more
doaj   +1 more source

Poor outcomes with treatment of hepatorenal syndrome type 1 with splancnic vasoconstrictors and albumin: report of seven cases and review of the literature Resultados adversos com o emprego de vasoconstritores esplâncnicos e albumina para tratamento da síndrome hepatorrenal do tipo 1: relato de sete casos e revisão da literatura

Arquivos de Gastroenterologia, 2009
CONTEXT: Treatment of hepatorenal syndrome type 1 (HRS-1) with splancnic vasoconstrictors and high-dose albumin has been associated with reversal of renal failure in approximately 60% to 80% of the cases in pilot or uncontrolled studies.
Jamile Rosário Kalil, Liv Aparicio Cerqueira, Daniel Silva Barbosa, Marina Pamponet Motta, Marília da Silva Nery, Paulo Lisboa Bittencourt   +5 more
doaj   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

Role of cyclooxygenase in the vascular responses to extremity cooling in Caucasian and African males [PDF]

, 2017
This is an accepted manuscript of an article published by Wiley in Experimental Physiology on 01/06/2017, available online: https://doi.org/10.1113/EP086186 The accepted version of the publication may differ from the final published version.© 2017 The ...
Adams, Bailey, Belvins, Burgess, Chotani, Chotani, Clare M. Eglin, Connor, Cowley, Cowley, Daanen, DeGroot, Dobnikar, Farnell, Feairheller, Foster, Freeman, Golden, Granberg, Gresele, Griendling, Heavey, Hechtman, Hodges, Iampietro, Jackson, James R. House, Jay, Johnson, Johnson, Kalinowski, Keatinge, Kenney, Keramidas, Kukreja, Lee, Maley, Maley, Maley, Matthew J. Maley, Mekjavic, Michael J. Tipton, Newman, O'Brien, Paton, Pergola, Ramstead, Rennie, Richards, Sawada, Serneri, Spealman, Thompson-Torgerson, Thomson, Tindall, Tyler, Ungley, Ungley, Vane, Vanhoutte, Wrenn   +60 more
core   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anaesthesia: An open label randomised controlled trial

Frontiers in Physiology, 2014
Background: During caesarean section spinal anaesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine.
Visti Torbjørn Foss, Kim Zillo Rokamp, Robin Daniel Christensen, Peter eNissen, Niels Henry Secher, Henning Bay Nielsen   +5 more
doaj   +1 more source

Nitrates for the Management of Acute Heart Failure Syndromes, A Systematic Review [PDF]

, 2016
© The Author(s) 2016Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS) yet with lack of robust evidence to support their use.
Farag, Mohamed, Gorog, Diana A, Shoaib, Ahmad   +2 more
core   +2 more sources

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source