Results 81 to 90 of about 19,396 (257)

Push-Dose Adrenaline versus Ephedrine for the Management of Intraoperative Hypotension: A Retrospective Observational Study

Bali Journal of Anesthesiology
Background: Intraoperative hypotension (IOH) is common during anesthesia and is associated with adverse postoperative outcomes. Ephedrine is widely used to treat acute IOH, while push-dose adrenaline has emerged as a potential alternative, offering rapid
Muhamad Rafiqi Hehsan, Chia Ying Chew, Kamaruddin Ibrahim, Mohammad Haizar Khan Haidar Khan   +3 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Reversible Cerebral Vasoconstriction Syndrome Associated with Ileostomy and Blood Transfusion in a Patient with Advanced Gastric Cancer: A Case Report and Review of the Literature

Journal of the Korean Society of Radiology
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by transient multifocal segmental arterial narrowing, and it is often accompanied by thunderclap headaches.
Ji-hye Yoo, Sam Soo Kim, Chang Mok Lim, Seong Heon Kim   +3 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Poor outcomes with treatment of hepatorenal syndrome type 1 with splancnic vasoconstrictors and albumin: report of seven cases and review of the literature Resultados adversos com o emprego de vasoconstritores esplâncnicos e albumina para tratamento da síndrome hepatorrenal do tipo 1: relato de sete casos e revisão da literatura

Arquivos de Gastroenterologia, 2009
CONTEXT: Treatment of hepatorenal syndrome type 1 (HRS-1) with splancnic vasoconstrictors and high-dose albumin has been associated with reversal of renal failure in approximately 60% to 80% of the cases in pilot or uncontrolled studies.
Jamile Rosário Kalil, Liv Aparicio Cerqueira, Daniel Silva Barbosa, Marina Pamponet Motta, Marília da Silva Nery, Paulo Lisboa Bittencourt   +5 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Loss of glomerular responses to vasoconstrictor agents in rabbits recovering from ARF

Kidney International, 1986
Glomerular responses to angiotensin II (AII), arginine vasopressin (AVP), and norepinephrine (NE) were estimated in rabbits recovering from uranium-mediated nephropathy or ischemic acute renal failure (ARF) to examine roles of intraglomerular events in resistance to ARF. Uranyl acetate (UA, 0.8 mg/kg) produced ARF in some animals but did not in others.
Ikuma, Katsuhito, Honda, Nishio, Hishida, Akira, Nagase, Mitsumasa   +3 more
openaire   +2 more sources

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Effect of phenylephrine vs. ephedrine on frontal lobe oxygenation during caesarean section with spinal anaesthesia: An open label randomised controlled trial

Frontiers in Physiology, 2014
Background: During caesarean section spinal anaesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine.
Visti Torbjørn Foss, Kim Zillo Rokamp, Robin Daniel Christensen, Peter eNissen, Niels Henry Secher, Henning Bay Nielsen   +5 more
doaj   +1 more source