Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine (ADMA) in the rat aorta [PDF]
<b>Background and purpose</b>: Previous work has shown that NG-monomethyl-l-arginine (l-NMMA) paradoxically inhibits basal, but not ACh-stimulated activity of nitric oxide in rat aorta.
Archer+29 more
core +3 more sources
Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core +2 more sources
Background Intraoperative hypotension is a risk factor for postoperative acute kidney injury (AKI). Elderly patients are susceptible due to reduced responses to acute hemodynamic changes.Aims Determine the association between hypotension identified from ...
Dilshan Ariyarathna+8 more
doaj +1 more source
Iatrogenic Takotsubo Cardiomyopathy Secondary to Norepinephrine by Continuous Infusion for Shock
Takotsubo cardiomyopathy is a condition characterized by transient left ventricular systolic and diastolic dysfunction, with a possible direct causal role of catecholamine in its pathophysiology.
Alfredo Vieira+2 more
doaj +1 more source
An investigation into the relationship between small intestinal fluid secretion and systemic arterial blood pressure in the anesthetized rat [PDF]
In the absence of an ability to absorb fluid by cellular uptake mechanisms, fluid movement in vivo from the perfused rat intestine is absorptive when the diastolic blood pressure is normal or very low but is secretory when blood pressure falls below ...
Lucas, Michael, Morrison, James
core +1 more source
Use of anesthetics associated to vasoconstrictors for dentistry in patients with cardiopathies: review of the literature published in the last decade [PDF]
Objective: The use of local anesthetics associated to vasoconstrictor agents in dentistry is thoroughly justified and is widely extended, but we cannot ignore the fact that anesthetic infiltration poses risk of complications throughout the dental ...
Corcuera Flores, José Ramón+4 more
core +1 more source
The Role of the ACE2/MasR Axis in Ischemic Stroke: New Insights for Therapy
Ischemic stroke remains the leading cause of neurologically based morbidity and mortality. Current stroke treatment is limited to two classes of FDA-approved drugs: thrombolytic agents (tissue plasminogen activator (tPA)) and antithrombotic agents ...
Mansoureh Barzegar+4 more
doaj +1 more source
Bioavailability, Antipsoriatic Efficacy and Tolerability of a New Light Cream with Mometasone Furoate 0.1% [PDF]
Mometasone furoate, a potent glucocorticoid (class III) with a favorable benefit/risk ratio, has emerged as a standard medication for the treatment of inflammatory skin disorders.
Ayres JW+30 more
core +1 more source
Background In randomized clinical controlled trials, the choice of usual care as the comparator may be associated with better clinician uptake of the study protocol and lead to more generalizable results. However, if care processes evolve to resemble the
Marie-Hélène Masse+15 more
doaj +1 more source
Role of cyclooxygenase in the vascular responses to extremity cooling in Caucasian and African males [PDF]
This is an accepted manuscript of an article published by Wiley in Experimental Physiology on 01/06/2017, available online: https://doi.org/10.1113/EP086186 The accepted version of the publication may differ from the final published version.© 2017 The ...
Adams+60 more
core +2 more sources