Results 61 to 70 of about 3,320,030 (364)

Statins and the vasculopathy of systemic sclerosis: potential therapeutic agents? [PDF]

, 2006
It has been postulated that endothelial cell injury is the initiating event in the pathogenesis of systemic sclerosis, causing attraction, attachment, migration and infiltration of activated T-cells and subsequent production of cytokines and growth ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

The clinical pharmacology of intranasal l-methamphetamine. [PDF]

, 2008
BackgroundWe studied the pharmacology of l-methamphetamine, the less abused isomer, when used as a nasal decongestant.Methods12 subjects self-administered l-methamphetamine from a nonprescription inhaler at the recommended dose (16 inhalations over 6 ...
Everhart, Tom, Foster, Elyse, Harris, Debra S, Jacob, Peyton, Jones, Reese T, McGlothlin, Dana, Mendelson, John E   +6 more
core   +2 more sources

The role of external broadcasting in a closed political system [PDF]

, 2011
This article investigates the role and impact of external broadcasting (radio and television) on a closed political system, through the example of the two post-war German states: the West German Federal Republic of Germany (FRG) and the East German ...
Andreas Scheu, Browne DR, Castells M., Corbin J., DeFleur ML, Der Spiegel, Hafez K., Hahn O., Hesse KR, Hopkins M., Hyman HH, Infratest, Infratest, Infratest, Infratest, Jansen M., Lindlof T., McQuail D., Merritt AJ, Merritt AJ, Meyen M., Michael Meyen, Parta RE, Perse EM   +23 more
core   +2 more sources

Vasoplegia treatments: the past, the present, and the future

Critical Care, 2018
Vasoplegia is a ubiquitous phenomenon in all advanced shock states, including septic, cardiogenic, hemorrhagic, and anaphylactic shock. Its pathophysiology is complex, involving various mechanisms in vascular smooth muscle cells such as G protein-coupled
Bruno Levy, Caroline Fritz, Elsa Tahon, Audrey Jacquot, Thomas Auchet, Antoine Kimmoun   +5 more
doaj   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül, Neriman Sıla Koç, Berrak Itır Aylı   +2 more
wiley   +1 more source

Terlipressin-related Ischaemic Necrosis of the Skin: A Rare Complication

European Journal of Case Reports in Internal Medicine, 2019
Terlipressin is used for the treatment of bleeding oesophageal varices and hepatorenal syndrome in patients with cirrhosis. Adverse effects are usually minimal.
Sara Simões Macedo, Cátia Cabral, António Novais, Mónica Teixeira, Anna Knock   +4 more
doaj   +1 more source

Use of anesthetics associated to vasoconstrictors for dentistry in patients with cardiopathies: review of the literature published in the last decade [PDF]

, 2012
Objective: The use of local anesthetics associated to vasoconstrictor agents in dentistry is thoroughly justified and is widely extended, but we cannot ignore the fact that anesthetic infiltration poses risk of complications throughout the dental ...
Corcuera Flores, José Ramón, Machuca Portillo, Guillermo, Serrera Figallo, María Angeles, Torres Lagares, Daniel, Velázquez Cayón, Rocío   +4 more
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The efficacy of hyperbaric oxygen therapy for skin perfusion following peripheral tissue injury due to usage of inotropes and vasopressors: a case report [PDF]

Clinical and Experimental Emergency Medicine
Hyperbaric oxygen therapy (HBOT) has garnered significant attention as a therapeutic modality with potential benefits across a variety of medical conditions, ranging from wound healing and ischemic conditions to neurologic disorders and radiation-induced
Nien Hsiu Suen, Chang Hae Pyo, Hyun Kyung Park, Keun Hong Park, Dongsun Choi   +4 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source