Microcirculation impairment and blood pressure in sepsis [PDF]
Medicinski Glasnik, 2009 Blood pressure is crucial for the tissue perfusion, oxygenation andelimination of metabolites in normal tissue. In septic patients itmay be altered by several mechanisms.
Domagoj Drenjančević +4 more
doaj
The role of endothelin-1 in pulmonary arterial hypertension. [PDF]
, 2014 Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
Chester, AH, Yacoub, MH
core +1 more source
Endothelin and the ischaemic heart [PDF]
, 2005 Soon after its identification as a powerful vasoconstrictor peptide, endothelin (ET-1) was implicated as a detrimental agent involved in determining the outcome of myocardial ischaemia and reperfusion.
Kane, K.A., McCabe, C., Wainwright, C.L.
core +1 more source
Modern views on the molecular and vascular mechanisms of preeclampsia
Ukrainian Scientific Medical Youth Journal, 2022 the article summarizes the arguments and counterarguments in the scientific discussion on the mechanisms of preeclampsia. The main purpose of this study is to summarize information about the molecular and vascular mechanisms of preeclampsia.
Tetiana Shumilina, Yaroslava Slyvka
doaj +1 more source
Cooperative and Competitive Biases for Multi-Agent Reinforcement Learning [PDF]
arXiv, 2021 Training a multi-agent reinforcement learning (MARL) algorithm is more challenging than training a single-agent reinforcement learning algorithm, because the result of a multi-agent task strongly depends on the complex interactions among agents and their interactions with a stochastic and dynamic environment.
arxiv
Fact-based Agent modeling for Multi-Agent Reinforcement Learning [PDF]
arXiv, 2023 In multi-agent systems, agents need to interact and collaborate with other agents in environments. Agent modeling is crucial to facilitate agent interactions and make adaptive cooperation strategies. However, it is challenging for agents to model the beliefs, behaviors, and intentions of other agents in non-stationary environment where all agent ...
arxiv
The effect of ethnicity on the vascular responses to cold exposure of the extremities [PDF]
, 2014 This is an accepted manuscript of an article published by Springer in European Journal of Applied Physiology on 01/08/2014, available online: https://doi.org/10.1007/s00421-014-2962-2 The accepted version of the publication may differ from the final ...
Eglin, CM +3 more
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The dual endothelin converting enzyme/neutral endopeptidase inhibitor SLV-306 (daglutril), inhibits systemic conversion of big endothelin-1 in humans [PDF]
, 2012 Aims - Inhibition of neutral endopeptidases (NEP) results in a beneficial increase in plasma concentrations of natriuretic peptides such as ANP.
Alison Seed +62 more
core +2 more sources
The Role of Adjuvant Acid Suppression on the Outcomes of Bleeding Esophageal Varices after Endoscopic Variceal Ligation. [PDF]
PLoS ONE, 2017 The impact of adjuvant acid suppression via proton pump inhibitors or histamine-2 receptor antagonists after endoscopic variceal ligation remains uncertain.
Cheng-Kun Wu +14 more
doaj +1 more source
Aging and aerobic fitness affect the contribution of noradrenergic sympathetic nerves to the rapid cutaneous vasodilator response to local heating [PDF]
, 2011 Sedentary aging results in a diminished rapid cutaneous vasodilator response to local heating. We investigated whether this diminished response was due to altered contributions of noradrenergic sympathetic nerves; assessing 1) the age-related decline and,
Alan D. Ruddock +6 more
core +1 more source