Results 21 to 30 of about 86,075 (269)

Physiological and Metabolic Adaptation to Heat Stress at Different Altitudes in Yaks

Metabolites, 2022
Yaks have strong adaptability to extremely cold and hypoxic conditions but are susceptible to high ambient temperature when yaks are raised in low-altitude areas during the high-temperature season.
Shuli Yang, Jinfeng Liu, Zhaobing Gu, Ping Liu, Qin Lan   +4 more
doaj   +1 more source

Role of aldehyde dehydrogenase in hypoxic vasodilator effects of nitrite in rats and humans [PDF]

, 2015
Hypoxic conditions favour the reduction of nitrite to nitric oxide (NO) to elicit vasodilatation, but the mechanism(s) responsible for bioconversion remains ill defined.
Alexander, Alexander, Angelo, Badejo, Bailey, Baliga, Basu, Chen, Cosby, D'Souza, Dejam, DiFabio, Doyle, Furchgott, Ghosh, Gladwin, Golwala, Greenstein, Huellner, Huffman, Irvine, Johansson, Keith, Kollau, Koppaka, Larsen, Li, Lundberg, Mackenzie, Madhani, Maher, Maher, Marti, Ormerod, Paneni, Pawson, Perlman, Pinder, Tiso, Totzeck   +39 more
core   +2 more sources

Hydroxysafflor Yellow A (HSYA) from Flowers of Carthamus tinctorius L. and Its Vasodilatation Effects on Pulmonary Artery

Molecules, 2012
Flowers of Carthamus tinctorius L. are traditionally used in China to treat cerebrovascular and cardiovascular diseases. Hydroxysafflor yellow A (HSYA), the main constituent of Carthamus tinctorius L.
Lijun Wu, Dan Yi, Minggang Chen, Chunyue Yu, Chenghua Han, Yuhua Bai, Ping Lu, Fa He   +7 more
doaj   +1 more source

The endothelial glycocalyx prefers albumin for evoking shear stress-induced, nitric oxide-mediated coronary dilatation [PDF]

, 2007
Background: Shear stress induces coronary dilatation via production of nitric oxide ( NO). This should involve the endothelial glycocalyx ( EG). A greater effect was expected of albumin versus hydroxyethyl starch ( HES) perfusion, because albumin seals ...
Bernhard F. Becker, Chang YS, Desjardins C, Dirk Bruegger, Gonzalez-Castillo C, Huxley VH, Joern O. Paul, Kuchan MJ, Leipert B, Markus Rehm, Matthias Jacob, Michael Loetsch, Mochizuki S, Mulivor AW, Peter Conzen, Platts SH, Pohl U, Pries AR, Risau W, Rubanyi GM, Siegel G, Ulrich Welsch, van Haaren P, Vink H, Vink H, Vink H   +25 more
core   +1 more source

D. russelii Venom Mediates Vasodilatation of Resistance Like Arteries via Activation of K_v and K_Ca Channels

Toxins, 2019
Russell’s viper (Daboia russelii) venom causes a range of clinical effects in humans. Hypotension is an uncommon but severe complication of Russell’s viper envenoming. The mechanism(s) responsible for this effect are unclear.
Rahini Kakumanu, Sanjaya Kuruppu, Lachlan D. Rash, Geoffrey K. Isbister, Wayne C. Hodgson, Barbara K. Kemp-Harper   +5 more
doaj   +1 more source

Vasorelaxation, Induced by Dictyota pulchella (Dictyotaceae), a Brown Alga, Is Mediated via Inhibition of Calcium Influx in Rats

Marine Drugs, 2011
This study aimed to investigate the cardiovascular effects elicited by Dictyota pulchella, a brown alga, using in vivo and in vitro approaches. In normotensive conscious rats, CH2Cl2/MeOH Extract (CME, 5, 10, 20 and 40 mg/kg) from Dictyota pulchella ...
Isac A. Medeiros, George E. C. Miranda, José M. Barbosa-Filho, Valdir A. Braga, Maria C. Alustau, Camila S. Figueiredo, Fabíola F. Furtado, Abrahão A. Oliveira-Filho, Natália T. Machado, Thyago M. Queiroz   +9 more
doaj   +1 more source

Reduction in jejunal fluid absorption in vivo through distension and cholinergic stimulation not attributable to enterocyte secretion [PDF]

, 2018
Jejunal fluid absorption in vivo was reduced by distension and by hydrostatic pressure and further declined on adding E. coli STa enterotoxin but no net fluid secretion was detected.
Graham, V., Kenward, H., Lucas, M., McColl, S., McNaughton, E., Sabir, S., Tainsh, P., Turkington, C., Watson, P.   +8 more
core   +1 more source

Potential health effects of Champagne wine consumption [PDF]

, 2011
Epidemiological studies have suggested an inverse correlation between red wine consumption and the incidence of cardiovascular and neurodegenerative disorders.
Corona, Giulia, Garnotel, Roselyne, Gillery, Philippe, Hercelin, Justine, Lovegrove, Julie A., Spencer, Jeremy P. E., Vauzour, David, Williams, Claire M.   +7 more
core   +1 more source

The Clinical Significance of Salusins in Systemic Sclerosis—A Cross-Sectional Study

Diagnostics, 2023
Background: Systemic sclerosis (SSc) is a connective tissue disease manifesting with progressive fibrosis of the skin and internal organs. Its pathogenesis is strictly associated with vascular disfunction and damage.
Joanna Nowaczyk, Leszek Blicharz, Michał Zawistowski, Mariusz Sikora, Michał Zaremba, Joanna Czuwara, Lidia Rudnicka   +6 more
doaj   +1 more source

Essential role for proteinase-activated receptor-2 in arthritis [PDF]

, 2003
Using physiological, pharmacological, and gene disruption approaches, we demonstrate that proteinase-activated receptor-2 (PAR-2) plays a pivotal role in mediating chronic inflammation. Using an adjuvant monoarthritis model of chronic inflammation, joint
Andrew J.H. Smith, Asokananthan, Damiano, Damiano, Elizabeth B. Kelso, Frances McGarry, Gary D. Hunter, John C. Lockhart, John S. McLean, Junichi Kawagoe, Lindner, Lu Jiang, Lynette Dunning, Plevin, Robert Ramage, Robin Plevin, Stephen E. Meek, Toru Kanke, William R. Ferrell, Yang   +19 more
core   +2 more sources