Results 111 to 120 of about 54,430 (317)

Endothelin-1 and Nitric Oxide levels in exudative age-related macular degeneration

open access: yesJournal of Ophthalmic & Vision Research, 2015
Purpose: To evaluate plasma levels of endothelin-1 (ET-1) and nitric oxide (NO) in patients with exudative age-related macular degeneration (AMD). Methods: In this study, ET-1 levels, as well as nitrite plus nitrate concentrations as an indicator of ...
Yuksel Totan   +4 more
doaj   +1 more source

Mihai Gheorghiade, MD-Life and Concepts [PDF]

open access: yes, 2018
How do you capture an idea, shape it, and then bring it into the world? Of his many talents, this ability was a fundamental characteristic of Mihai Gheorghiade.
Butler, Javed   +3 more
core   +1 more source

Uncovering the impact of the cardiovascular system on cerebrovascular health using MRI

open access: yesExperimental Physiology, EarlyView.
Abstract Human cerebrovasculature is finely tuned to enable local changes in blood flow to meet the brain's demands, whilst protecting the brain from systemic changes in blood pressure, both acutely during a heartbeat and chronically over time. This review summarises cerebrovascular structure and function, their role in disease and neurodegeneration ...
Ian D. Driver, Kevin Murphy
wiley   +1 more source

Role of S1P‐ and Rho‐kinase signalling in age‐related myogenic tone deficiency in murine resistance arteries

open access: yesExperimental Physiology, EarlyView.
Abstract Ageing is a risk factor for cardiovascular and neurodegenerative diseases. The myogenic response in resistance arteries is responsible for basal (myogenic) tone and blood flow autoregulation. G‐protein‐coupled receptors and G12/RhoA/Rho kinase are implicated in myogenic tone (MT), and we aimed to clarify their role in pressure sensing and ...
Gry Freja Skovsted   +11 more
wiley   +1 more source

Evaluation of Nitrosyl Ruthenium Complexes Entrapped in an Oil-In-Water Emulsion as Vasodilator Agents [PDF]

open access: bronze, 2008
Mario Marchesi   +6 more
openalex   +1 more source

Cardiovascular, respiratory and splenic responses to rebreathing and apnoea during exercise

open access: yesExperimental Physiology, EarlyView.
Abstract We investigated integrative physiological responses to eupnoeic exercise (EX), rebreathing exercise (RB), dynamic apnoea (DA) and dynamic apnoea with cold‐water face immersion (DAFI) in 20 healthy participants. Trials involved non‐steady‐state cycle exercise at 60 W for an average duration of 66 s.
Theodore Dotevall   +5 more
wiley   +1 more source

Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Oxygen and carbon dioxide enter the body via breathing; in the brain astrocytes play a key role balancing oxygen delivery with carbon dioxide removal. Abstract If we consider neurons like muscles during exercise, the demand for oxygen (O2) and carbon dioxide (CO2) elimination is constantly changing.
Isabel N. Christie
wiley   +1 more source

Hypoxia and the cytoskeleton

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

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