Results 111 to 120 of about 30,809 (165)

The Effect of Local Vasodilating Agents

1977
Contrary to the previously widely held concept that nitroglycerin is contraindicated in acute myocardial infarction, it has recently been shown that the administration of nitroglycerin to patients with acute myocardial infarction and elevated left ventricular filling pressures results in a reduction in filling pressure and in an increase in cardiac ...
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β-Blocking Agents with Vasodilating Action

Journal of Cardiovascular Pharmacology, 1992
beta-Adrenoceptor-blocking drugs in current use can be separated into two main groups: those nonselective and those selective for beta 1-receptors. Members of each group reduce cardiac output and lead to an increase in peripheral resistance with a concomitant reduction in blood flow.
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Beta-blocking agents with vasodilator activity

Journal of Hypertension, 1993
Use of non-selective beta-blockers: Non-selective beta-blockers reduce blood pressure by reducing cardiac output. They have a proven record of efficacy, alone or in combination with other drug classes, in the treatment of hypertension, ischemic heart disease and some tachyarrhythmias.
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Pharmacokinetics of Vasodilating Agents

1986
Studies on the metabolism of nitroglycerin in various animal species have shown distinct differences making it problematic to extrapolate from experimental animal data to humans. Needleman et al. (1972) found complete inactivation of nitrates following oral administration in rats as a result of the first-pass effect in the liver.
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Cardiovascular Pharmacology of the Vasodilator-Cardiotonic Agent, 349U85

Journal of Cardiovascular Pharmacology, 1992
349U85 is a chemically novel, nonglycoside, noncatecholamine cardiotonic-vasodilator agent with a unique cardiovascular profile in vitro and in vivo. 349U85 and milrinone, 10(-6) to 3 x 10(-5) M each, produce concentration-dependent increases in tension development of 33-60% and 37-60%, respectively, with corresponding 5-18% and 17-55% increases in ...
R P, Steffen, W B, Wastila
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Mechanism of Action of Vasodilating Agents

1988
The development of heart failure is accompanied by the activation of neuroendocrine compensatory mechanisms (see chapter “Endocrine response to heart failure”). Although these responses are initially aimed at preserving cardiovascular homeostasis, they eventually lead to a further deterioration of myocardial performance due to excessive ...
J. Biollaz, A. Munafo, T. Buclin
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Vasodilating Agents in Augmentation of Skin Flap Survival

Otolaryngology–Head and Neck Surgery, 1979
Skin flap necrosis is a serious problem in reconstructive head and neck surgery. Currently, the only clinically effective means of preventing flap necrosis is delay. Hypothesized mechanisms of delayed and experimental methods of increasing flap survival are discussed.
J M, Toomey, J M, Conoyer, J H, Ogura
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The effectiveness of local injections of vasodilating agents to produce vasodilation in subcutaneous tissue in rabbits

Clinical Physiology, 1985
Summary. . The isotope washout method has been widely used to study characteristics of the microcirculation in localized vascular beds. Some of these studies have used local injections of vasodilating agents to maximally dilate the vascular bed. This study was undertaken to determine the agent most effective in producing this critical vasodilation.A ...
H J, Duncan, I B, Faris, N J, DeYoung
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The Treatment of Shock with Vasodilating Agents

1985
It is a great honour for me to have been asked to describe the medical field in which I worked in the early 1950s, which led to a medical change in the approach to the treatment of shock. In those years change in more than one respect took place in the treatment of severely ill patients.
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Effects of Vasodilator Antihypertensive Agents on Renal Function

Journal of Cardiovascular Pharmacology, 1987
The effects of calcium antagonist and noncalcium antagonist vasodilator antihypertensive agents were examined using renal clearance, hemodynamic, and micropuncture techniques in anesthetized normotensive dogs, rats, and conscious spontaneously hypertensive rats.
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