Results 11 to 20 of about 51,762 (264)

The Role of the ACE2/MasR Axis in Ischemic Stroke: New Insights for Therapy

Biomedicines, 2021
Ischemic stroke remains the leading cause of neurologically based morbidity and mortality. Current stroke treatment is limited to two classes of FDA-approved drugs: thrombolytic agents (tissue plasminogen activator (tPA)) and antithrombotic agents ...
Mansoureh Barzegar, Karen Y. Stokes, Oleg Chernyshev, Roger E. Kelley, Jonathan S. Alexander   +4 more
doaj   +1 more source

Aging and aerobic fitness affect the contribution of noradrenergic sympathetic nerves to the rapid cutaneous vasodilator response to local heating [PDF]

, 2011
Sedentary aging results in a diminished rapid cutaneous vasodilator response to local heating. We investigated whether this diminished response was due to altered contributions of noradrenergic sympathetic nerves; assessing 1) the age-related decline and,
Alan D. Ruddock, Angus JA, Garry A. Tew, Gary J. Hodges, James Moss, John M. Saxton, Markos Klonizakis   +6 more
core   +1 more source

Aminophylline shortage and current recommendations for reversal of vasodilator stress: an ASNC information statement endorsed by SCMR

Journal of Cardiovascular Magnetic Resonance, 2018
Pharmacologic reversal of serious or intolerable side effects (SISE) from vasodilator stress is an important safety and comfort measure for patients experiencing such effects. While typically performed using intravenous aminophylline, recurrent shortages
Aiden Abidov, Vasken Dilsizian, Rami Doukky, W. Lane Duvall, Christopher Dyke, Michael D. Elliott, Fadi G. Hage, Milena J. Henzlova, Nils P. Johnson, Ronald G. Schwartz, Gregory S. Thomas, Andrew J. Einstein   +11 more
doaj   +1 more source

Portopulmonary hypertension practice patterns after liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose, Elizabeth J. Kopras, Shimul A. Shah, Jean M. Elwing   +3 more
wiley   +1 more source

Systolic blood pressure reduction during the first 24 h in acute heart failure admission: friend or foe? [PDF]

, 2017
Aims: Changes in systolic blood pressure (SBP) during an admission for acute heart failure (AHF), especially those leading to hypotension, have been suggested to increase the risk for adverse outcomes.
Bourge, Robert C, Cleland, John GF, Cotter, Gad, Davison, Beth A, Edwards, Christopher, Jondeau, Guillaume, Kobrin, Isaac, McMurray, John JV, Metra, Marco, Milo, Olga, O'Connor, Christopher M, Parker, John D, Rainisio, Maurizio, Senger, Stefanie, Teerlink, John R, Torre-Amione, Guillermo, van Veldhuisen, Dirk J, VERITAS Investigators   +17 more
core   +5 more sources

Nitrates for the Management of Acute Heart Failure Syndromes, A Systematic Review [PDF]

, 2016
© The Author(s) 2016Intravenous nitrates are widely used in the management of acute heart failure syndrome (AHFS) yet with lack of robust evidence to support their use.
Farag, Mohamed, Gorog, Diana A, Shoaib, Ahmad   +2 more
core   +2 more sources

Vascular responses of the extremities to transdermal application of vasoactive agents in Caucasian and African descent individuals [PDF]

, 2015
This is an accepted manuscript of an article published by Springer in European Journal of Applied Physiology on 04/04/2015, available online: https://doi.org/10.1007/s00421-015-3164-2 The accepted version of the publication may differ from the final ...
AC Shore, Army Medical surveillance activity, AT Koutsavlis, B Endrich, B Waeber, BJ Kim, C Cardillo, C Cardillo, CC Ungley, CC Ungley, Clare M. Eglin, CM Stein, CM Stein, CR Anderson, CS Thompson-Torgerson, D Bylund, D Miller, DA Rosenbaum, DF Kahn, DL Feairheller, DS Jones, DW DeGroot, E Clark, E Mata-Greenwood, FSC Golden, GA Conway, HA Daanen, HC Parkington, HP Rang, J Gainer, J Jia, J Jia, J Lundberg, James R. House, JE Burgess, JE Ramsay, JM Johnson, JP Noon, K Hope, K Komori, K Sauerstein, KK Griendling, KW Russell, L Ekenvall, L Kalinowski, LA Holowatz, LA Holowatz, M Honda, M Roustit, M Schmelz, M Shibasaki, MA Chotani, MA Chotani, MA Hashmi, Matthew J. Maley, ME Pueyo, Michael J. Tipton, MJ Easter, MJ Maley, MS Taylor, N Melikian, O Wilson, RF Furchgott, RG Hendry, RT Grant, RT Grant, SJ Duffy, SJ Morris, SJ Sarnoff, SR Bailey, T Lewis, TJ Cleophas, TM Mäkinen, WH Candler   +73 more
core   +4 more sources

Drug treatment of hypertension: focus on vascular health [PDF]

, 2016
Hypertension, the most common preventable risk factor for cardiovascular disease and death, is a growing health burden. Serious cardiovascular complications result from target organ damage including cerebrovascular disease, heart failure, ischaemic heart
Cameron, Alan C., Lang, Ninian N., Touyz, Rhian M.   +2 more
core   +1 more source

Impact of a TAK-1 inhibitor as a single or as an add-on therapy to riociguat on the metabolic reprograming and pulmonary hypertension in the SUGEN5416/hypoxia rat model

Frontiers in Pharmacology, 2023
Background: Despite increasing evidence suggesting that pulmonary arterial hypertension (PAH) is a complex disease involving vasoconstriction, thrombosis, inflammation, metabolic dysregulation and vascular proliferation, all the drugs approved for PAH ...
Daniel Morales-Cano, Daniel Morales-Cano, Daniel Morales-Cano, Daniel Morales-Cano, Daniel Morales-Cano, Jose Luis Izquierdo-García, Jose Luis Izquierdo-García, Jose Luis Izquierdo-García, Bianca Barreira, Bianca Barreira, Bianca Barreira, Sergio Esquivel-Ruiz, Sergio Esquivel-Ruiz, Sergio Esquivel-Ruiz, Maria Callejo, Maria Callejo, Maria Callejo, Rachele Pandolfi, Rachele Pandolfi, Rachele Pandolfi, Palmira Villa-Valverde, Palmira Villa-Valverde, Ignacio Rodríguez, Ignacio Rodríguez, Angel Cogolludo, Angel Cogolludo, Angel Cogolludo, Jesus Ruiz-Cabello, Jesus Ruiz-Cabello, Jesus Ruiz-Cabello, Francisco Perez-Vizcaino, Francisco Perez-Vizcaino, Francisco Perez-Vizcaino, Laura Moreno, Laura Moreno, Laura Moreno   +35 more
doaj   +1 more source

Role of cyclooxygenase in the vascular response to locally delivered acetylcholine in Caucasian and African descent individuals [PDF]

, 2017
This is an accepted manuscript of an article published by Elsevier in Microvascular Research on 17/01/2017, available online: https://doi.org/10.1016/j.mvr.2017.01.005 The accepted version of the publication may differ from the final published version.©
Eglin, CM, House, JR, Maley, MJ, Tipton, MJ   +3 more
core   +3 more sources