Results 161 to 170 of about 115,075 (345)

Enhancing Multi‐Enzyme Cascade Activity in Metal‐Organic Frameworks via Controlled Enzyme Encapsulation

open access: yesSmall, EarlyView.
A sequential strategy is developed for controlled encapsulation of multi‐enzymes within a core‐shell structure in metal‐organic frameworks. The results demonstrate that multi‐enzyme cascade activity is significantly enhanced due to the optimal spatial arrangement, increased surface area, and improved enzymes conformation. Additionally, the encapsulated
Wenqing Fan   +4 more
wiley   +1 more source

Long‐term displacement behavior under sustained load for post‐installed rebar connections and bonded anchors

open access: yesStructural Concrete, EarlyView.
Abstract Post‐installed rebar connections and bonded fasteners are frequently used in the construction industry for connecting structural concrete elements or for anchoring structural steel elements to the base material concrete. The main goal of this contribution is to compare the long‐term displacement behavior under sustained load between the two ...
Elisabeth Stierschneider   +2 more
wiley   +1 more source

Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials

open access: yesIntensive Care Medicine, 2019
M. Nagendran   +8 more
semanticscholar   +1 more source

Words to live by: Using medic impressions to identify the need for prehospital lifesaving interventions

open access: yesAcademic Emergency Medicine, EarlyView.
Abstract Background Prehospital emergencies require providers to rapidly identify patients’ medical condition and determine treatment needs. We tested whether medics’ initial, written impressions of patient condition contain information that can help identify patients who require prehospital lifesaving interventions (LSI) prior to or during transport ...
Aaron C. Weidman   +7 more
wiley   +1 more source

Drinking motives and alcohol sensitivity mediate multidimensional genetic influences on alcohol use behaviors

open access: yesAlcohol, Clinical and Experimental Research, EarlyView.
Alcohol use behaviors (AUBs) are heritable, and research has identified many regions of the genome that correlate with individual differences in AUBs. However, there are many steps between DNA and behavior where these genes could have an effect. Here, we tested whether genes are associated with AUBs via intermediate measures of personality, alcohol ...
Jeanne E. Savage   +58 more
wiley   +1 more source

Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

open access: yesPsychiatry and Clinical Neurosciences, Volume 76, Issue 12, Page 620-632, December 2022., 2022
Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more likely to appear in SD than in early‐life depression, but it remains unclear whether the pathophysiology is different. The prevalence of dementia increases with aging, and the underlying pathophysiological processes in the preclinical phase begin even before ...
Ito Kawakami   +4 more
wiley   +1 more source

Folding, misfolding, and regulation of intracellular traffic of G protein‐coupled receptors involved in the hypothalamic–pituitary–gonadal axis

open access: yesAndrology, EarlyView.
Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre   +5 more
wiley   +1 more source

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