Results 41 to 50 of about 25,819 (299)

Asymmetric Synthesis of Atropisomeric Amines via Transaminase‐Catalyzed Dynamic Kinetic Resolution

Advanced Synthesis &Catalysis, EarlyView.
A dynamic kinetic resolution approach is developed for the atroposelective synthesis of heterobiaryl primary amines. Using transaminases and leveraging Lewis acid‐base interactions to induce racemization, a variety of axially chiral primary amines are produced in high yields and enantioselectivities.
Juan M. Coto‐Cid, Patricia Rodríguez‐Salamanca, Christian M. Heckmann, Caroline E. Paul, Joaquín López‐Serrano, Rosario Fernández, José M. Lassaletta, Valentín Hornillos, Gonzalo de Gonzalo   +8 more
wiley   +1 more source

Caesarean myomectomy in a tertiary health facility in southern Nigeria: Report of a series of successful cases

Ibom Medical Journal
Uterine leiomyoma is the commonest tumour of the uterus with incidence of about 20-40% in reproductive age women. Treatment of leiomyoma during caesarean section remains a controversial subject in spite of advancement in medical treatment.
Eyong EM, Okpebri KO, Omoronyia EE, Emechebe CI, Ekabua JE   +4 more
doaj   +1 more source

Analytical methods for the quantitative determination of oxytocin [PDF]

, 2010
Oxytocin is a clinically important nonapeptide that is used for the induction and/or augmentation of labor and is normally administered as a slow intravenous infusion diluted with normal saline or Ringer’s lactate solution. Oxytocin is also indicated for
Chaibva, F A, Walker, Roderick
core   +1 more source

Genome‐scale Metabolic Modeling Guided Escherichia coli Engineering for De Novo Biosynthesis of Chrysanthemic Acid

Advanced Science, EarlyView.
Genome‐scale metabolic modeling is preceded to the engineered E. coli cell factory for the de novo biosynthesis of biopesticide chrysanthemic acid. The debranching strategy redirects metabolic flux, enhancing precursor and target compound production.
Jiangpeng Yu, Kelin Cheng, Shenyang Qu, Jie Wang, Xun Wang, Cheng Zhao, Wei Li   +6 more
wiley   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

In vitro binding and receptor-mediated activity of terlipressin at vasopressin receptors V1 and V2

Journal of Experimental Pharmacology, 2017
Khurram Jamil,1 Stephen Chris Pappas,2 Krishna R Devarakonda1 1Clinical Development, Mallinckrodt Pharmaceuticals, Bedminster, 2Orphan Therapeutics, LLC, Lebanon, NJ, USA Abstract: Terlipressin, a synthetic, systemic vasoconstrictor with selective ...
Jamil K, Pappas SC, Devarakonda KR
doaj  

Rhodamine-B labeled peptide hormone evaluation by thin layer chromatography [PDF]

, 2010
A novel thin layer chromatographic procedure was devised to evaluate the activity of rhodamine-B tagged peptide hormone such as vasopressin & octreotide. Peptide hormones viz.
A. Babu Vimalanathan, Manoj G. Tyagi, Felsi Priyadarsini, Aniket Kumar,
core   +2 more sources

Dynamics of calcitonin gene-related peptide-like cells changes in the lungs of two-kidney, one-clip rats [PDF]

, 2012
Taking into consideration renal hypertension-induced homeostatic disorders and the key role of calcitonin gene-related peptide (CGRP) in many, systemic functions regulating systems, a question arises as to what an extent arterial hypertension affects the
Arciszewska, E., Kasacka, I.
core   +3 more sources

Monolayer Amorphous Carbon: Unlocking Disorder‐Induced Lithiophilicity

Advanced Science, EarlyView.
Atomic‐scale disorder in monolayer amorphous carbon generates abundant Li binding sites. Combined contact angle, electrochemical, and Density Functional Theory analyses show how this broad distribution of binding energies lowers the contact angle to around 30°, reduces the nucleation overpotential, and yields uniform lithium deposition.
Lu Shi, Hanning Zhang, Artem K. Grebenko, Ruslan Yamaletdinov, Rejaul SK, Ranjith Shivajirao, Zheng Jue Tong, Sergey Luchkin, Hongji Zhang, Konstantin V. Iakoubovskii, Alena A. Alekseeva, Andrei Starkov, Carlo M. Orofeo, Junhao Lin, Kazutomo Suenaga, Chee‐Tat Toh, Remi Mahfouz, Talah M. Tayeb, Nada Qari, Stefan Adams, Bent Weber, Oleg V. Yazyev, Barbaros Özyilmaz   +22 more
wiley   +1 more source

A Modular Biosensor Platform for the Detection of Plastic Monomers and the Engineering of Promiscuous Amidases Toward Challenging Substrates

Advanced Science, EarlyView.
A luciferase is used as biosensor for aldehydes, produced enzymatically from different monomeric building blocks of plastics like polyurethanes (PUs). The screening platform is used to monitor esterase, amidase, and urethanase activity and to guide the selection of enzyme variants with improved hydrolytic activities toward difficult to hydrolyze ...
Ina Somvilla, Hannah Meier, Florian Oehlschläger, Hannes Meinert, Lena Koch, Patrick Ihrle, Katharina M. Mehnert, Morten Flieger, Jonas Boß, Marco Seifert, Dominique Böttcher, Uwe T. Bornscheuer, Thomas Bayer   +12 more
wiley   +1 more source