Results 101 to 110 of about 58,275 (313)

Medical Knowledge Integration Into Reinforcement Learning Algorithms for Dynamic Treatment Regimes

open access: yesInternational Statistical Review, EarlyView.
Summary The goal of precision medicine is to provide individualised treatment at each stage of chronic diseases, a concept formalised by dynamic treatment regimes (DTR). These regimes adapt treatment strategies based on decision rules learned from clinical data to enhance therapeutic effectiveness.
Sophia Yazzourh   +3 more
wiley   +1 more source

Hemoglobina pos-operatoria inmediata en cirugía cardiovascular como predictor de requerimiento de vasopresores e inotrópicos en la Unidad de Cuidados Intensivos Immediate postoperative hemoglobin in cardiovascular surgery as predictor of vasopressors and inotropes in Intensive Care Unit

open access: yesRevista Colombiana de Cardiología, 2011
Antecedentes: los pacientes sometidos a cirugía cardiovascular representan un desafío de manejo en la unidad de cuidados intensivos debido principalmente al estrés hemodinámico que se deriva de la cirugía y a las comorbilidades que se presentan con ...
Mabel Gómez   +4 more
doaj  

Methylene blue therapy in addition to standard treatment for acute-phase septic shock: a pilot randomized controlled trial

open access: yesFrontiers in Medicine
PurposeMethylene blue (MB) has been used to increase blood pressure in patients with septic shock by acting on guanylate cyclase and nitric oxide synthase.ObjectiveTo determine whether the administration of MB to patients in the initial phase of septic ...
Fabio Luis-Silva   +19 more
doaj   +1 more source

Delayed Admission to the Intensive Care Unit Is Associated With Increased Mortality Risk in Critically Ill Patients: A Prospective Cohort Study

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine the impact of delays in intensive care unit (ICU) admission on patient outcomes, specifically clinical deterioration and mortality among patients transferred from the emergency department (ED) or general wards following acute deterioration in an Australian public hospital.
Shivaprasad Anagi   +8 more
wiley   +1 more source

Does Magnesium Sulfate Alter the Maternal Cardiovascular Response to Vasopressor Agents in Gravid Ewes? [PDF]

open access: bronze, 1991
Susan L. Sipes   +5 more
openalex   +1 more source

A mini‐review of chronic suppression of the hypothalamic–pituitary–adrenal axis in animals with P‐glycoprotein deficiency

open access: yesJournal of Small Animal Practice, EarlyView.
This mini‐review describes the pathophysiology of the disrupted hypothalamic–pituitary–adrenal axis in dogs, and probably cats, with the MDR1 (ABCB1) mutation, ABCB1‐1Δ in dogs and ABCB11930‐1931del TC in cats. Clinical consequences in affected animals are discussed and therapeutic interventions to consider are presented.
K. L. Mealey
wiley   +1 more source

ARC in Critical Ill OLT Recipients: True Prevalence, Risk Factors, and Impact on Early Aggressive PK/PD Target Non‐Attainment of CI Beta‐Lactam Therapy for Posttransplant Gram‐Negative Infections

open access: yesTransplant Infectious Disease, EarlyView.
Augmented renal clearance (ARC) represents a quite prevalent condition among critical orthotopic liver transplant recipients (23.2%). ARC is associated with different demographics and clinical features and significantly affects the attainment of aggressive beta‐lactams pharmacokinetic/pharmacodynamic targets despite the administration of standard ...
Milo Gatti   +6 more
wiley   +1 more source

Inotropes and vasopressors [PDF]

open access: bronze, 2017
Lenko Šarić   +2 more
openalex   +1 more source

Timing of intrapartum transfusion among obstetric patients, stratified by admission and discharge haemoglobin, relative to anaesthesia care: A retrospective cohort study

open access: yesTransfusion Medicine, EarlyView.
Abstract Background We previously validated and implemented criteria for auditing anaesthesiologists with intraoperative transfusion based on low median blood loss of the surgical procedure or absence of anaemia before transfusion. However, obstetrical cases were excluded during implementation, as the peripartum blood management protocol does not ...
Franklin Dexter   +2 more
wiley   +1 more source

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