Results 61 to 70 of about 39,660 (237)

Uninformed consent

Journal of Hospital Medicine, EarlyView.
John Talia
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Risk Factors of Blood Culture Positivity and Mortality in Bloodstream Infections: A Population‐Based Study of Patients With B‐Cell Malignancies

European Journal of Haematology, EarlyView.
ABSTRACT Background Bloodstream infections remain a major cause of mortality among cancer patients. Pathogen surveillance and risk stratification tools are key to improved management. This study describes trends in causative pathogens and explores risk factors for positive blood cultures (PBCs) and post‐infection mortality in cancer patients.
Mathias Holmsgaard Eskesen, Alexander Djupnes Fuglkjær, Tarec Christoffer El‐Galaly, Paw Jensen, Izabela Ewa Nielsen, Laurids Østergaard Poulsen, Mikkel Runason Simonsen, Kirstine Kobberøe Søgaard   +7 more
wiley   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source

At the heart of home‐based care: multidisciplinary heart failure management in a quaternary centre's community programmes

Internal Medicine Journal, EarlyView.
Abstract Background Heart failure (HF) is a frequent cause of hospital admissions, carrying a high risk of hospital readmission and mortality. Alfred Health General Medicine Hospital in the Home (GM‐HITH) and Hospital Admission Risk Program (HARP) offer multidisciplinary HF care to multimorbid patients in bed‐substitution and non‐admitted community ...
Elana Forbes, Ingrid Hopper, Cathy Corbett, Felice Borghmans, Emma O'Donnell, Ana Slavnic, Genevieve Harvey, Elizabeth Rochford, Archana Thayaparan   +8 more
wiley   +1 more source

Hemoglobina pos-operatoria inmediata en cirugía cardiovascular como predictor de requerimiento de vasopresores e inotrópicos en la Unidad de Cuidados Intensivos Immediate postoperative hemoglobin in cardiovascular surgery as predictor of vasopressors and inotropes in Intensive Care Unit

Revista Colombiana de Cardiología, 2011
Antecedentes: los pacientes sometidos a cirugía cardiovascular representan un desafío de manejo en la unidad de cuidados intensivos debido principalmente al estrés hemodinámico que se deriva de la cirugía y a las comorbilidades que se presentan con ...
Mabel Gómez, Iván Rendón, Luis E Silva, Carlos Sánchez, Andrés F Buitrago   +4 more
doaj  

Methylene blue therapy in addition to standard treatment for acute-phase septic shock: a pilot randomized controlled trial

Frontiers in Medicine
PurposeMethylene blue (MB) has been used to increase blood pressure in patients with septic shock by acting on guanylate cyclase and nitric oxide synthase.ObjectiveTo determine whether the administration of MB to patients in the initial phase of septic ...
Fabio Luis-Silva, Mayra Gonçalves Menegueti, Leandro Moreira Peres, Corina dos Reis Sepeda, Maria Cecília Jordani, Fabiola Mestriner, Bruno Cesar Petroski-Moraes, Joaquim Pedro Brito-de-Sousa, Ismael Artur Costa-Rocha, Bruna Lemos Cruz, Mariana Dermínio Donadel, Felipe Barizza de Souza, Gustavo Henrique Martins Reis, Fernando Bellissimo-Rodrigues, Anibal Basile-Filho, Christiane Becari, Christiane Becari, Paulo Roberto Barbosa Evora, Olindo Assis Martins-Filho, Maria Auxiliadora-Martins   +19 more
doaj   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

Internal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop, Tanya Ravipati, Steven Mileto, Eugene Athan, Dena Lyras, Ravindranath Tiruvoipati   +5 more
wiley   +1 more source

Effect of vertical distance between the heart base and the cuff on arterial blood pressure measurements using PetMAP in anaesthetised dogs

Journal of Small Animal Practice, EarlyView.
Objectives To evaluate how variations in limb positioning, when compared with standard position at the heart base, affect oscillometric arterial blood pressure measurements in 22 anaesthetised healthy dogs. Materials and Methods The thoracic vertical depth was measured in each dog from the caudal angle of the scapula to the body of the sternum caudal ...
R. McConomy, H. Pinnok, C. Adami
wiley   +1 more source

Reassessing Perioperative Management Strategies for Phaeochromocytoma and Paraganglioma Resections

ANZ Journal of Surgery, EarlyView.
Jun Wei Chong, Simon Harper, Stephanie Manning, Rosemary M. Hall   +3 more
wiley   +1 more source