Results 101 to 110 of about 223,260 (263)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Locally trivial quantum vector bundles and associated vector bundles
We define locally trivial quantum vector bundles (QVB) and QVB associated to locally trivial quantum principal fibre bundles. There exists a differential structure on the associated vector bundle coming from the differential structure on the principal bundle, which allows to define connections on the associated vector bundle associated to connections ...
Calow, Dirk, Matthes, Rainer
openaire +2 more sources
Linear transports along paths in vector bundles. III. Curvature and torsion [PDF]
Bozhidar Z. Iliev
openalex +1 more source
Stable geometric dimension of vector bundles over even-dimensional real projective spaces [PDF]
Martin Bendersky +2 more
openalex +1 more source
Strong exceptional sequences of vector bundles on certain Fano varieties [PDF]
Mihai Halic
openalex +1 more source
Coordinates for the Universal Moduli Space of Holomorphic Vector Bundles [PDF]
Jørgen Ellegaard Andersen +1 more
openalex +1 more source

