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Understanding how ecological interactions affect vector-borne disease dynamics is crucial in the context of rapid biodiversity loss and increased emerging vector-borne diseases.
Lifan Chen +3 more
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Zika Virus Mosquito Vectors: Competence, Biology, and Vector Control [PDF]
Zika virus (ZIKV) (Flaviviridae, Flavivirus) has become one of the most medically important mosquito-borne viruses because of its ability to cause microcephaly in utero and Guillain-Barré syndrome in adults. This virus emerged from its sylvatic cycle in Africa to cause an outbreak in Yap, Federated States of Micronesia in 2007, French Polynesia in 2014,
Elizabeth B, Kauffman, Laura D, Kramer
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Background Transmission dynamics of arboviruses like Zika virus are often evaluated by vector competence (the proportion of infectious vectors given exposure) and the extrinsic incubation period (EIP, the time it takes for a vector to become infectious),
E. Handly Mayton +3 more
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Estimating the magnitude and direction of altered arbovirus transmission due to viral phenotype. [PDF]
Vectorial capacity is a measure of the transmission potential of a vector borne pathogen within a susceptible population. Vector competence, a component of the vectorial capacity equation, is the ability of an arthropod to transmit an infectious agent ...
Rebecca C Christofferson +1 more
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Mutualist-Provisioned Resources Impact Vector Competency [PDF]
Parasites elicit several physiological changes in their host to enhance transmission. Little is known about the functional association between parasitism and microbiota-provisioned resources typically dedicated to animal hosts and how these goods may be rerouted to optimize parasite development.
Rita V. M. Rio +7 more
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Implications of mosquito metabolism on vector competence
AbstractMosquito‐borne diseases (MBDs) annually kill nearly half a million people. Due to the lack of effective vaccines and drugs on most MBDs, disease prevention relies primarily on controlling mosquitoes. Despite huge efforts having been put into mosquito control, eco‐friendly and sustainable mosquito‐control strategies are still lacking and ...
Li Gao, Wenxu Yang, Jingwen Wang
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Immunization by replication-competent controlled herpesvirus vectors [PDF]
ABSTRACTReplication-competent controlled virus vectors were derived from virulent HSV-1 wildtype strain 17syn+ by placing one or two replication-essential genes under the stringent control of a gene switch that is co-activated by heat and an antiprogestin. Upon activation of the gene switch, the vectors replicate in infected cells with an efficacy that
Bloom, David C. +3 more
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Background Vector management programs rely on knowledge of the biology and genetic make-up of mosquitoes. Anopheles stephensi is a major invasive urban malaria vector, distributed throughout the Indian subcontinent and Middle East, and has recently been ...
Chaitali Ghosh +10 more
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Geographic Partitioning of Dengue Virus Transmission Risk in Florida
Dengue viruses (DENVs) cause the greatest public health burden globally among the arthropod-borne viruses. DENV transmission risk has also expanded from tropical to subtropical regions due to the increasing range of its principal mosquito vector, Aedes ...
Caroline J. Stephenson +6 more
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Dengue virus (DENV) is a highly prevalent vector-borne virus that causes life-threatening illnesses to humans worldwide. The development of a tool to control vector populations has the potential to reduce the burden of DENV.
Abdullah A. Alomar +6 more
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