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The Insect Microbiome Modulates Vector Competence for Arboviruses [PDF]
Diseases caused by arthropod-borne viruses (arboviruses), such as Dengue, West Nile, and Chikungunya, constitute a major global health burden and are increasing in incidence and geographic range. The natural microbiota of insect vectors influences various aspects of host biology, such as nutrition, reproduction, metabolism, and immunity, and recent ...
Natapong Jupatanakul +2 more
openaire +3 more sources
Arthropod-borne viruses (arboviruses) require replication across a wide range of temperatures to perpetuate. While vertebrate hosts tend to maintain temperatures of approximately 37°C-40°C, arthropods are subject to ambient temperatures which can have a ...
Reyes A Murrieta +9 more
doaj +1 more source
Immunization by replication-competent controlled herpesvirus vectors [PDF]
ABSTRACT Replication-competent controlled virus vectors were derived from virulent HSV-1 wildtype strain 17 syn + by placing one or two replication-essential genes under the stringent control of a gene switch that is co-activated by heat and an antiprogestin.
Bloom, David C. +3 more
openaire +2 more sources
Background Temperature is known to induce changes in mosquito physiology, development, ecology, and in some species, vector competence for arboviruses. Since colonized mosquitoes are reared under laboratory conditions that can be significantly different ...
Dodson Brittany L +2 more
doaj +1 more source
Dengue (DENV), yellow fever, chikungunya, and Zika virus transmission to humans by a mosquito host is confounded by both intrinsic and extrinsic variables.
David W. Severson, Susanta K. Behura
doaj +1 more source
Zika virus outbreak in the Pacific: Vector competence of regional vectors
In 2013, Zika virus (ZIKV) emerged in French Polynesia and spread through the Pacific region between 2013 and 2017. Several potential Aedes mosquitoes may have contributed to the ZIKV transmission including Aedes aegypti, the main arbovirus vector in the region, and Aedes polynesiensis, vector of lymphatic filariasis and secondary vector of dengue ...
Calvez, Elodie +8 more
openaire +6 more sources
Mosquitoes as Suitable Vectors for Alphaviruses
Alphaviruses are arthropod-borne viruses and are predominantly transmitted via mosquito vectors. This vector preference by alphaviruses raises the important question of the determinants that contribute to vector competence.
Elisa X. Y. Lim +3 more
doaj +1 more source
Aedes albopictus is a competent vector of Zika virus: A meta-analysis.
BACKGROUND:Much work has been done in recent years to determine the vector competence of Aedes albopictus (Skuse) for Zika virus (ZIKV). If competent, Ae.
Benjamin A McKenzie +2 more
doaj +1 more source
Vector or host competence can be defined as the ability of an individual to become infected and subsequently transmit a pathogen. Assays to measure competence play a key part in the assessment of the factors affecting mosquito-borne virus transmission ...
Jennifer S Lord, Michael B Bonsall
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Arthropods Under Pressure: Stress Responses and Immunity at the Pathogen-Vector Interface
Understanding what influences the ability of some arthropods to harbor and transmit pathogens may be key for controlling the spread of vector-borne diseases.
Kristin L. Rosche +4 more
doaj +1 more source

